Short Description

NTRK1 rearrangements have been shown to be involved in thyroid carcinogenesis. Several studies show that NTRK1 rearrangements may be associated with a worse clinical course when compared with NTRK1 rearrangement-negative Papillary Thyroid Carcinomas. The treatment of patients with NTRK fusion-positive cancers with a NTRK inhibitor, such as the FDA approved drugs Larotrectinib or Entrectinib, is associated with high response rates regardless of NTRK gene, fusion partner, and tumor type. Hence, detection of NTRK1 rearrange-ments by in situ Hybridization may be of prognostic and therapeutic significance.

PreTest Information

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Detail Description

FISH - NTRK 1 GENE REARRANGEMENT ASSAY Test Cost, Symptoms & Diagnosis

Are you or a loved one experiencing unexplained symptoms or a rare form of cancer? One potential cause could be a rearrangement of the NTRK 1 gene. Fortunately, DNA Labs India offers a FISH - NTRK 1 Gene Rearrangement Assay test to diagnose this condition. In this blog, we'll cover the cost of the test, symptoms, and diagnosis process.

What is NTRK 1 Gene Rearrangement?

NTRK 1 gene rearrangement occurs when the NTRK 1 gene on chromosome 1 breaks apart and fuses with another gene. This fusion can cause uncontrolled cell growth, leading to cancer.

It's important to note that NTRK 1 rearrangement is rare, accounting for less than 1% of all cancer cases. However, for those affected, it can be a devastating diagnosis.

What are the Symptoms of NTRK 1 Gene Rearrangement?

The symptoms of NTRK 1 gene rearrangement can vary depending on the type of cancer it causes. However, some common symptoms include:

• Abdominal pain
• Bone pain
• Difficulty breathing
• Fatigue
• Headaches
• Loss of appetite
• Nausea
• Weight loss

If you're experiencing any of these symptoms, it's important to speak with your doctor to determine the cause and appropriate treatment.

How is NTRK 1 Gene Rearrangement Diagnosed?

The FISH - NTRK 1 Gene Rearrangement Assay is a diagnostic test that can detect NTRK 1 gene rearrangement. This test uses fluorescent probes to identify the fusion of the NTRK 1 gene with other genes.

To perform the test, a small tissue sample is collected from the patient and analyzed in a laboratory. The results of the test can help doctors determine the appropriate treatment for the patient.

What is the Cost of the FISH - NTRK 1 Gene Rearrangement Assay Test?

The cost of the FISH - NTRK 1 Gene Rearrangement Assay test at DNA Labs India is INR 7,020. This cost includes the analysis of the tissue sample and the interpretation of the results by a qualified medical professional.

While this test may seem expensive, it's important to remember that a proper diagnosis is crucial for effective treatment. Additionally, some insurance plans may cover the cost of the test.

Conclusion

If you or a loved one are experiencing unexplained symptoms or have been diagnosed with a rare form of cancer, it's important to consider NTRK 1 gene rearrangement as a potential cause. The FISH - NTRK 1 Gene Rearrangement Assay test offered by DNA Labs India can help diagnose this condition and guide appropriate treatment. Contact DNA Labs India today to learn more.

Remember, early detection and treatment can make all the difference in your health and well-being.

NTRK1 rearrangements have been shown to be involved in thyroid carcinogenesis. Several studies show that NTRK1 rearrangements may be associated with a worse clinical course when compared with NTRK1 rearrangement-negative Papillary Thyroid Carcinomas. The treatment of patients with NTRK fusion-positive cancers with a NTRK inhibitor, such as the FDA approved drugs Larotrectinib or Entrectinib, is associated with high response rates regardless of NTRK gene, fusion partner, and tumor type. Hence, detection of NTRK1 rearrange-ments by in situ Hybridization may be of prognostic and therapeutic significance.