Short Description

Monosomy 7 or del(7q) are among the most common recurrent chromosome abnormality. This aberration occurs in 8% of de novo Acute Myeloid Leukemia (AML), in 5-10% of de novo patients with Myelodysplastic Syndrome (MDS), and in approximately 50% of therapy-related Myeloid neoplasms. Myeloid malignancies with monosomy 7 or del(7q) respond poorly to chemotherapy and are associated with an unfavorable prognosis.

PreTest Information

Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Detail Description

FISH-MONOSOMY 7 / del7q31 FOR AML / MDS Test: Cost, Symptoms, Diagnosis

Acute Myeloid Leukemia (AML) and Myelodysplastic Syndromes (MDS) are blood disorders that affect the bone marrow and blood cells. These disorders are caused by genetic mutations that affect the normal functioning of blood cells. One such genetic mutation is FISH-MONOSOMY 7 / del7q31, which is commonly found in patients with AML and MDS. DNA Labs India offers a specialized FISH test for the diagnosis of this mutation.

Symptoms of AML and MDS

The symptoms of AML and MDS can vary depending on the severity of the disease. Some common symptoms include:

• Fatigue
• Shortness of breath
• Pale skin
• Easy bruising or bleeding
• Frequent infections
• Weight loss
• Bone pain

If you are experiencing any of these symptoms, it is important to consult a doctor for proper diagnosis and treatment.

Diagnosis of FISH-MONOSOMY 7 / del7q31

The FISH-MONOSOMY 7 / del7q31 test is a specialized genetic test that helps in the diagnosis of AML and MDS. This test involves the use of fluorescent probes that bind to specific genes in the DNA. The probes are then visualized under a microscope to detect any abnormalities in the genes. This test is highly sensitive and can detect even small genetic mutations that may be missed by other tests.

Cost of FISH-MONOSOMY 7 / del7q31 Test

The cost of the FISH-MONOSOMY 7 / del7q31 test at DNA Labs India is INR 6000. This test is covered by most insurance plans and can also be paid for out-of-pocket.

Conclusion

The FISH-MONOSOMY 7 / del7q31 test is a specialized genetic test that helps in the diagnosis of AML and MDS. If you are experiencing any symptoms of these blood disorders, it is important to consult a doctor for proper diagnosis and treatment. The cost of the FISH test at DNA Labs India is affordable and can be covered by insurance. For more information on this test, please contact DNA Labs India.

Monosomy 7 or del(7q) are among the most common recurrent chromosome abnormality. This aberration occurs in 8% of de novo Acute Myeloid Leukemia (AML), in 5-10% of de novo patients with Myelodysplastic Syndrome (MDS), and in approximately 50% of therapy-related Myeloid neoplasms. Myeloid malignancies with monosomy 7 or del(7q) respond poorly to chemotherapy and are associated with an unfavorable prognosis.