Short Description

Myeloid and lymphoid neoplasms with FGFR1 are generally aggressive and may present as MPN, AML, T- or B-Lymphoblastic leukemia / ALL or Mixed phenotype acute leukemia.

PreTest Information

Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.

Detail Description

FISH - FGFR1 (8p12) GENE REARRANGEMENT Test: Cost, Symptoms, and Diagnosis

FGFR1 (8p12) gene rearrangement is a rare genetic disorder that occurs due to the abnormality in chromosome 8. This rearrangement results in the production of a protein that causes uncontrolled growth of cells, leading to cancer. The FISH - FGFR1 (8p12) gene rearrangement test is a diagnostic tool that helps in detecting this disorder. In this blog, we will discuss the cost, symptoms, and diagnosis of the FISH - FGFR1 (8p12) gene rearrangement test.

Cost of FISH - FGFR1 (8p12) gene rearrangement test

The cost of the FISH - FGFR1 (8p12) gene rearrangement test in India is around INR 6,000. However, the cost may vary depending on the location and the diagnostic center.

Symptoms of FGFR1 (8p12) gene rearrangement

The symptoms of FGFR1 (8p12) gene rearrangement may vary from person to person. Some common symptoms include:

• Unexplained weight loss
• Persistent fever
• Fatigue
• Shortness of breath
• Night sweats
• Loss of appetite
• Swollen lymph nodes
• Pain in the bones

If you experience any of these symptoms, it is advisable to consult a doctor immediately.

Diagnosis of FGFR1 (8p12) gene rearrangement

The FISH - FGFR1 (8p12) gene rearrangement test is a diagnostic tool that helps in detecting this disorder. It is a simple and non-invasive test that can be performed on a blood or bone marrow sample.

The test involves the use of fluorescent probes that bind to the specific region of the chromosome 8 where the FGFR1 (8p12) gene is located. The probes emit light signals that can be analyzed under a microscope. If the probes bind to the specific region of the chromosome 8, it indicates that the gene rearrangement has occurred.

If the test is positive, further tests may be required to determine the extent of the cancer and the appropriate treatment plan.

Conclusion

If you experience any of the symptoms mentioned above, it is important to consult a doctor immediately. The FISH - FGFR1 (8p12) gene rearrangement test is a simple and non-invasive diagnostic tool that can help in detecting this disorder. The cost of the test may vary depending on the location and the diagnostic center. Early diagnosis and treatment can increase the chances of recovery and improve the quality of life.

For more information on the FISH - FGFR1 (8p12) gene rearrangement test, contact DNA Labs India.

Myeloid and lymphoid neoplasms with FGFR1 are generally aggressive and may present as MPN, AML, T- or B-Lymphoblastic leukemia / ALL or Mixed phenotype acute leukemia.