Short Description

NGS genetic DNA test detecets for variant and mutation detection in FERMT3 gene for Leukocyte adhesion deficiency type 3

PreTest Information

Clinical History of Patient who is going for FERMT3 Gene Leukocyte adhesion deficiency type 3 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with FERMT3 Gene Leukocyte adhesion deficiency type 3 NGS Genetic DNA Test gene FERMT3

Detail Description

FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test

Leukocyte Adhesion Deficiency (LAD) is a rare genetic disorder that affects the immune system's ability to fight infections. LAD Type 3 is caused by mutations in the FERMT3 gene and is characterized by severe bacterial infections, impaired wound healing, and bleeding disorders.

DNA Labs India offers FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test at a cost of INR 20,000. This test uses Next-Generation Sequencing (NGS) technology to sequence the FERMT3 gene and detect any mutations that may be present.

Symptoms of FERMT3 Gene Leukocyte Adhesion Deficiency Type 3

• Recurrent bacterial infections
• Delayed wound healing
• Bleeding disorders
• Increased susceptibility to infections
• Failure to thrive
• Delayed growth

Diagnosis of FERMT3 Gene Leukocyte Adhesion Deficiency Type 3

Diagnosis of FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 involves genetic testing to identify any mutations in the FERMT3 gene. NGS Genetic DNA Test offered by DNA Labs India can detect any mutations in the FERMT3 gene and confirm the diagnosis of LAD Type 3.

If you or your child are experiencing any of the symptoms mentioned above, it is important to get tested for LAD Type 3. Early diagnosis and treatment can prevent complications and improve the quality of life of the affected individual.

Conclusion

DNA Labs India offers FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test at an affordable cost of INR 20,000. This test can help diagnose LAD Type 3 and provide early intervention to prevent complications. If you suspect that you or your child may have LAD Type 3, contact DNA Labs India to schedule a test.

Leukocyte Adhesion Deficiency Type 3 (LAD3), also known as LAD-III, is a rare genetic disorder that affects the immune system's ability to fight infections. It is caused by mutations in the FERMT3 gene (also known as Kindlin-3), which plays a crucial role in the adhesion of immune cells (leukocytes) to blood vessel walls and other cell surfaces. This adhesion is essential for immune cells to migrate to sites of infection and inflammation.

Symptoms of LAD3 can include recurrent bacterial and fungal infections, delayed wound healing, gum inflammation (gingivitis), and other immune-related issues due to the impaired function of white blood cells.

An NGS (Next-Generation Sequencing) genetic DNA test for the FERMT3 gene involves sequencing the DNA to identify any mutations or variations within the gene that could be linked to Leukocyte Adhesion Deficiency Type 3. This testing can help diagnose the condition and identify individuals who carry mutations in the FERMT3 gene.

If you suspect that you or someone you know may have LAD3 or if there's a family history of the condition, it's important to consult with an immunologist, hematologist, or medical geneticist who specializes in immune disorders. They can guide you through the genetic testing process, interpret the results, and provide appropriate recommendations for management and treatment based on the specific genetic findings. Treatment may involve managing infections, providing immune system support, and other strategies to address the immune system dysfunction associated with LAD3.