Short Description

NGS genetic DNA test detecets for variant and mutation detection in FANCB gene for Fanconi anemia type B

PreTest Information

Clinical History of Patient who is going for FANCB Gene Fanconi anemia type B NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Fanconi anemia type B

Detail Description

FANCB Gene Fanconi Anemia Type B NGS Genetic DNA Test Cost INR 20000: Symptoms and Diagnosis

Fanconi Anemia (FA) is a rare genetic disorder that affects the bone marrow, causing it to produce abnormal blood cells. FA is caused by mutations in one of the 22 known FA genes. One of these genes is FANCB, which is responsible for Fanconi Anemia type B. A genetic test for FANCB mutations can help diagnose Fanconi Anemia type B. In this blog, we will discuss the symptoms of Fanconi Anemia type B, the diagnosis process, and the cost of the FANCB gene NGS genetic DNA test in India.

Symptoms of Fanconi Anemia Type B

Fanconi Anemia type B is a rare form of FA and is caused by mutations in the FANCB gene. Symptoms of FA type B may include:

• Abnormal blood cell counts
• Bone marrow failure
• Increased risk of leukemia and other cancers
• Abnormalities in skeletal development
• Congenital abnormalities (such as kidney or heart defects)
• Hypersensitivity to DNA-damaging agents (such as chemotherapy)

Because FA is a genetic disorder, symptoms may be present at birth or may not appear until later in life.

Diagnosing Fanconi Anemia Type B

If a healthcare provider suspects that a patient has FA, they will likely perform a blood test to check for abnormal blood cell counts. If the patient has abnormal blood cell counts, a genetic test may be ordered to determine if there are mutations in one of the known FA genes, including FANCB. A genetic counselor may also be involved in the diagnosis process to help the patient and their family understand the implications of a positive diagnosis.

The Cost of the FANCB Gene NGS Genetic DNA Test in India

NGS (Next-Generation Sequencing) is a newer and more advanced method of genetic testing that can be used to analyze multiple genes at once. The cost of the FANCB gene NGS genetic DNA test in India is approximately INR 20000. However, the cost may vary depending on the laboratory and location. It is important to note that genetic testing may not be covered by insurance, so patients should check with their insurance provider before undergoing testing.

Conclusion

Fanconi Anemia type B is a rare genetic disorder that can have serious implications for patients and their families. If you suspect that you or someone you know may have FA type B, it is important to speak with a healthcare provider and consider genetic testing. The FANCB gene NGS genetic DNA test can help diagnose FA type B and costs approximately INR 20000 in India. By understanding the symptoms and diagnosis process for FA type B, patients and their families can take steps to manage the condition and improve their quality of life.