Short Description

NGS genetic DNA test detecets for variant and mutation detection in FAN1 gene for Interstitial nephritis karyomegalic

PreTest Information

Clinical History of Patient who is going for FAN1 Gene Interstitial nephritis karyomegalic NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with FAN1 Gene Interstitial nephritis karyomegalic NGS Genetic DNA Test gene FAN1

Detail Description

FAN1 Gene Interstitial Nephritis Karyomegalic NGS Genetic DNA Test – Symptoms, Diagnosis, and Cost

Interstitial nephritis is a medical condition that affects the kidneys' tissues and can be caused by various factors, such as infections, drugs, and autoimmune disorders. The FAN1 gene is associated with a specific type of interstitial nephritis called karyomegalic interstitial nephritis. This condition is inherited in an autosomal recessive manner, meaning both parents must carry the mutated gene for their child to develop the disease.

Symptoms of Karyomegalic Interstitial Nephritis

The symptoms of karyomegalic interstitial nephritis can vary from person to person, but some common signs include:

• Decreased urine output
• Swelling in the legs, ankles, and feet
• High blood pressure
• Weakness and fatigue
• Shortness of breath
• Weight gain
• Nausea and vomiting

If you experience any of these symptoms, it is important to consult a doctor immediately.

Diagnosis of Karyomegalic Interstitial Nephritis

The diagnosis of karyomegalic interstitial nephritis involves various tests and procedures. A doctor may perform a physical examination and order blood and urine tests to check for abnormalities. Imaging tests, such as ultrasound, CT scan, or MRI, can also be used to visualize the kidneys and identify any abnormalities.

A kidney biopsy may be necessary to confirm the diagnosis. During this procedure, a small piece of kidney tissue is removed and examined under a microscope to look for signs of interstitial nephritis.

NGS Genetic DNA Test for FAN1 Gene

A Next-Generation Sequencing (NGS) genetic DNA test can be used to detect mutations in the FAN1 gene associated with karyomegalic interstitial nephritis. This test involves analyzing the patient's DNA to identify any abnormalities in the FAN1 gene.

The NGS genetic DNA test is a highly accurate and reliable diagnostic tool, and it can provide important information for patients and their families. Knowing whether a patient has a mutated FAN1 gene can help with early diagnosis and treatment, as well as provide important information for family planning.

Cost of NGS Genetic DNA Test for FAN1 Gene

The cost of the NGS genetic DNA test for the FAN1 gene can vary depending on the laboratory and location. In India, the cost of this test is typically around INR 20,000.

While the cost of genetic testing may seem high, it is important to consider the potential benefits. Early diagnosis and treatment can help improve outcomes and quality of life for patients with karyomegalic interstitial nephritis. Additionally, genetic testing can provide important information for family planning and help prevent the spread of inherited diseases.

Conclusion

Karyomegalic interstitial nephritis is a rare genetic condition that can cause serious kidney damage. Early diagnosis and treatment are critical for improving outcomes and quality of life. The NGS genetic DNA test for the FAN1 gene can provide important information for patients and their families, and it is a highly accurate and reliable diagnostic tool. While the cost of genetic testing may seem high, it is important to consider the potential benefits for patients and future generations.

At DNA Labs India, we offer a wide range of genetic testing services, including the NGS genetic DNA test for the FAN1 gene. Our experienced team of genetic counselors and laboratory technicians can provide personalized and confidential testing services to help you make informed decisions about your health.