Short Description

NGS genetic DNA test detecets for variant and mutation detection in F2 gene for Factor II deficiency

PreTest Information

Clinical History of Patient who is going for F2 Gene Factor II deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Factor II deficiency

Detail Description

F2 Gene Factor II Deficiency NGS Genetic DNA Test Cost INR: 20,000 Symptoms Diagnosis

Factor II, also known as prothrombin, is a protein involved in blood clotting. Factor II deficiency is a rare genetic disorder that affects the ability of the blood to clot normally. It is caused by a mutation in the F2 gene, which provides instructions for making factor II.

Factor II deficiency can be inherited in an autosomal recessive pattern, which means that an individual must inherit a mutated F2 gene from both parents to develop the condition. It can also occur as a spontaneous mutation.

Symptoms of Factor II Deficiency

Many people with factor II deficiency do not experience any symptoms. However, in some cases, individuals may experience:

• Bruising easily
• Bleeding that is difficult to stop
• Nosebleeds
• Heavy menstrual bleeding
• Bleeding after dental procedures or surgery
• Bleeding in the gastrointestinal tract

Diagnosing Factor II Deficiency

Factor II deficiency is diagnosed through a blood test that measures the level of factor II in the blood. In some cases, genetic testing may be done to confirm the diagnosis and identify the specific mutation in the F2 gene.

NGS Genetic DNA Test for Factor II Deficiency

Next-generation sequencing (NGS) is a powerful tool for identifying genetic mutations that cause factor II deficiency. This test can identify mutations in the F2 gene and other genes involved in blood clotting.

The cost of an NGS genetic DNA test for factor II deficiency in India is typically around INR 20,000.

Who Should Consider an NGS Genetic DNA Test?

NGS genetic DNA testing for factor II deficiency may be recommended for individuals who have a family history of the condition or who have symptoms of abnormal bleeding or clotting. It may also be recommended for individuals who have an unexplained history of thrombosis (blood clots).

Conclusion

Factor II deficiency is a rare genetic disorder that can affect the ability of the blood to clot normally. Next-generation sequencing genetic DNA testing can help identify mutations in the F2 gene and other genes involved in blood clotting. If you have a family history of factor II deficiency or symptoms of abnormal bleeding or clotting, talk to your healthcare provider about whether an NGS genetic DNA test may be right for you.

For more information and to schedule an NGS genetic DNA test, contact DNA Labs India today.