Short Description

NGS genetic DNA test detecets for variant and mutation detection in F13A1 gene for Factor XIIIA deficiency

PreTest Information

Clinical History of Patient who is going for F13A1 Gene Factor XIIIA deficiency NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with F13A1 Gene Factor XIIIA deficiency NGS Genetic DNA Test gene F13A1

Detail Description

DNA Labs India: F13A1 Gene Factor XIIIA Deficiency NGS Genetic DNA Test Cost INR 20,000

Factor XIIIA deficiency, also known as F13A1 gene deficiency, is a rare genetic disorder that affects the blood clotting process. It is caused by mutations in the F13A1 gene, which provides instructions for making a protein called coagulation factor XIII. This protein plays a crucial role in the final stages of blood clotting, helping to stabilize the clot and prevent bleeding.

People with F13A1 gene deficiency have a higher risk of bleeding and bruising, particularly after injury or surgery. They may also experience abnormal bleeding during menstruation or childbirth. In some cases, F13A1 gene deficiency can lead to more serious complications such as intracranial hemorrhage or joint bleeds.

Symptoms of F13A1 Gene Factor XIIIA Deficiency

The symptoms of F13A1 gene deficiency can vary widely depending on the severity of the disorder. Some people may have no symptoms at all, while others may experience:

• Easy bruising or bleeding
• Excessive bleeding during menstruation or childbirth
• Bleeding into joints or muscles, causing pain and swelling
• Bleeding in the brain, leading to headaches, seizures, or other neurological symptoms

Diagnosis of F13A1 Gene Factor XIIIA Deficiency

F13A1 gene deficiency can be diagnosed through a genetic DNA test. This test analyzes a person's DNA to look for mutations in the F13A1 gene. It is typically performed using next-generation sequencing (NGS) technology, which allows for more accurate and comprehensive analysis of DNA sequences.

If a person is suspected of having F13A1 gene deficiency based on their symptoms or family history, their doctor may recommend genetic testing. The test involves taking a sample of the person's DNA, usually through a blood or saliva sample. The sample is then sent to a laboratory for analysis.

Cost of F13A1 Gene Factor XIIIA Deficiency NGS Genetic DNA Test in India

The cost of F13A1 gene deficiency NGS genetic DNA testing in India varies depending on the laboratory and location. On average, the cost is around INR 20,000.

Conclusion

F13A1 gene deficiency is a rare genetic disorder that can cause abnormal bleeding and bruising. If you or a loved one are experiencing symptoms of F13A1 gene deficiency or have a family history of the disorder, it may be worth considering genetic DNA testing. Talk to your doctor or a genetic counselor to learn more about your options.

DNA Labs India provides accurate and reliable F13A1 gene deficiency NGS genetic DNA testing services. Contact us today to schedule a test or learn more about our services.