Short Description

Autoantibodies are directed against the keratinocyte cell surface in patients with Pemphigus vulgaris. Approximately 50% of patients with Bullous pemphigoid express autoantibodies directed against the basement membtane of stratified squamous epithelium. There is a correlation between titre and disease activity.

PreTest Information

Overnight fasting is preferred.

Detail Description

Understanding the Epidermal (Pemphigus) Antibody IFA in Dilutions Test

Epidermal (Pemphigus) Antibody IFA in Dilutions Test is a diagnostic test that helps in the identification of pemphigus vulgaris, a rare autoimmune disorder which causes blistering on the skin and mucous membranes. The test is performed to detect the presence of antibodies that attack the epidermis, which is the outermost layer of the skin.

Symptoms of Pemphigus Vulgaris

The symptoms of pemphigus vulgaris include:

• Blisters on the skin and mucous membranes, which may be painful and itchy
• Crusts and sores on the skin and mucous membranes
• Difficulty in eating and swallowing due to blistering in the mouth and throat
• Scarring and discoloration of the skin

Diagnosis of Pemphigus Vulgaris

The diagnosis of pemphigus vulgaris is made through a combination of clinical examination and laboratory tests. A skin biopsy is often performed to confirm the diagnosis by examining the tissue under a microscope. Additionally, blood tests are performed to detect the presence of antibodies that attack the epidermis.

Epidermal (Pemphigus) Antibody IFA in Dilutions Test

The Epidermal (Pemphigus) Antibody IFA in Dilutions Test is a blood test that detects the presence of antibodies against the epidermal cells. The test is performed by diluting the patient's serum and incubating it with epidermal cells on a slide. The slide is then examined under a microscope to look for the presence of antibodies that bind to the epidermal cells.

Test Cost

The cost of the Epidermal (Pemphigus) Antibody IFA in Dilutions Test is INR 5500.

Conclusion

The Epidermal (Pemphigus) Antibody IFA in Dilutions Test is a valuable tool in the diagnosis of pemphigus vulgaris. Early diagnosis and treatment can help prevent complications and improve the quality of life for patients. If you are experiencing symptoms of pemphigus vulgaris, it is important to consult a dermatologist for a proper diagnosis and treatment plan.

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