Short Description

NGS genetic DNA test detecets for variant and mutation detection in ELAC2 gene for Prostate cancer, hereditary type 2, susceptibility to

PreTest Information

Clinical History of Patient who is going for ELAC2 Gene Prostate cancer, hereditary type 2, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ELAC2 Gene Prostate cancer, hereditary type 2, susceptibility to NGS Genetic DNA Test gene ELAC2

Detail Description

ELAC2 Gene Prostate Cancer: Hereditary Type 2 Susceptibility and NGS Genetic DNA Test Cost in India

Prostate cancer is one of the most common types of cancer in men. According to the American Cancer Society, about 1 in 8 men will be diagnosed with prostate cancer during their lifetime. While most cases of prostate cancer are not hereditary, some families have a higher risk of developing the disease due to a genetic mutation in the ELAC2 gene.

ELAC2 Gene and Prostate Cancer

The ELAC2 gene provides instructions for making a protein called RNase Z, which is involved in the processing of RNA molecules. Mutations in the ELAC2 gene have been associated with an increased risk of developing prostate cancer, particularly in men with a family history of the disease.

Hereditary prostate cancer accounts for about 5-10% of all cases of prostate cancer. In families with a history of the disease, the risk of developing prostate cancer is two to three times higher than in the general population.

Hereditary Type 2 Prostate Cancer

Hereditary prostate cancer is classified into two types: type 1 and type 2. Type 1 is characterized by an autosomal dominant inheritance pattern, which means that a mutation in a single gene can increase the risk of developing prostate cancer. Type 2, on the other hand, is a more complex form of hereditary prostate cancer that involves multiple genetic factors.

ELAC2 gene mutations are associated with hereditary type 2 prostate cancer. Other genes that have been linked to this form of the disease include BRCA1, BRCA2, HOXB13, and ATM.

NGS Genetic DNA Test for ELAC2 Gene Mutations

If you have a family history of prostate cancer, you may be at increased risk of developing the disease. Genetic testing can help identify mutations in the ELAC2 gene and other genes associated with hereditary prostate cancer.

Next-generation sequencing (NGS) is a type of genetic test that can analyze multiple genes at once. This type of test can identify mutations in the ELAC2 gene as well as other genes associated with hereditary type 2 prostate cancer.

Symptoms and Diagnosis of Prostate Cancer

Prostate cancer may not cause any symptoms in its early stages. As the cancer grows, it may cause symptoms such as:

• Frequent urination, especially at night
• Difficulty starting or stopping urination
• Weak or interrupted urine flow
• Blood in the urine or semen
• Pain or discomfort in the pelvic area

If you are experiencing any of these symptoms, it is important to see a doctor for an evaluation. Prostate cancer can be diagnosed through a variety of tests, including:

• Prostate-specific antigen (PSA) test
• Digital rectal exam (DRE)
• Transrectal ultrasound (TRUS)
• Prostate biopsy

NGS Genetic DNA Test Cost in India

The cost of NGS genetic DNA testing for ELAC2 gene mutations and other genes associated with hereditary prostate cancer may vary depending on the testing provider. In India, the cost of NGS genetic testing can range from INR 20,000 to INR 50,000.

Conclusion

Prostate cancer is a common type of cancer in men, and those with a family history of the disease may be at increased risk due to a genetic mutation in the ELAC2 gene. NGS genetic testing can help identify mutations in this gene and other genes associated with hereditary prostate cancer. If you are experiencing symptoms of prostate cancer or have a family history of the disease, talk to your doctor about genetic testing and other screening options.

Remember, early detection and treatment can improve your chances of a successful outcome.