Short Description

NGS genetic DNA test detecets for variant and mutation detection in DSPP gene for Deafness, autosomal dominant type 39, with dentinogenesis type 1

PreTest Information

Clinical History of Patient who is going for SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SLC52A3 Gene Brown-Vialetto-Van Laere syndrome 1 NGS Genetic DNA Test gene SLC52A6

Detail Description

DSPP Gene Deafness: Symptoms, Diagnosis and NGS Genetic DNA Test Cost

Deafness is a common condition that affects millions of people worldwide. There are various causes of deafness, including genetic factors. One of the genes associated with deafness is the DSPP gene, which is responsible for dentinogenesis type 1 and autosomal dominant type 39.

What is the DSPP gene?

The DSPP gene is located on chromosome 4 and encodes for dentin sialophosphoprotein, a protein that is essential for the formation of dentin, a hard tissue that makes up the bulk of teeth. Mutations in the DSPP gene can lead to various dental disorders, including dentinogenesis type 1.

DSPP gene deafness

In addition to dental disorders, mutations in the DSPP gene can also cause deafness. This type of deafness is known as autosomal dominant type 39. Autosomal dominant means that only one copy of the mutated gene is needed to cause the condition.

Symptoms of DSPP gene deafness

The symptoms of DSPP gene deafness can vary from person to person. Some individuals may experience mild hearing loss, while others may be completely deaf. The severity of the hearing loss is often dependent on the specific mutation in the DSPP gene.

Diagnosis of DSPP gene deafness

DSPP gene deafness can be diagnosed through genetic testing. Next-generation sequencing (NGS) is a type of genetic testing that can identify mutations in the DSPP gene. NGS is a highly sensitive and specific test that can detect even small mutations in the gene.

NGS genetic DNA test cost

The cost of NGS genetic DNA testing for DSPP gene deafness can vary depending on the laboratory performing the test. In India, the cost of the test is typically around INR 20,000.

Conclusion

DSPP gene deafness is a rare genetic condition that can cause varying degrees of hearing loss. Genetic testing, such as NGS, can be used to diagnose the condition. If you suspect that you or a loved one may have DSPP gene deafness, it is important to seek medical advice and consider genetic testing to confirm the diagnosis.

At DNA Labs India, we offer a range of genetic testing services, including NGS for DSPP gene deafness. Our team of experienced geneticists and technicians use the latest technology to provide accurate and reliable results. Contact us today to learn more about our services and how we can help you.