Short Description

NGS genetic DNA test detecets for variant and mutation detection in DSG1 gene for Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis and hyper IgE

PreTest Information

Clinical History of Patient who is going for DSG1 Gene Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis and hyper IgE NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with DSG1 Gene Erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis and hyper IgE NGS Genetic DNA Test gene DSG1

Detail Description

DSG1 Gene Erythroderma: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

DSG1 gene erythroderma is a rare inherited skin disorder that affects the skin's ability to function normally. It is characterized by redness and scaling of the skin, thickening of the palms and soles, hair loss, and elevated levels of IgE in the blood. This condition is caused by a mutation in the DSG1 gene, which encodes a protein called desmoglein 1 that helps hold skin cells together.

Symptoms

The symptoms of DSG1 gene erythroderma typically appear at birth or in the first few weeks of life. The most common symptoms include:

• Redness and scaling of the skin
• Thickening of the palms and soles
• Hair loss
• Elevated levels of IgE in the blood
• Itching and burning of the skin

Individuals with DSG1 gene erythroderma may also experience recurrent skin infections, nail abnormalities, and dental problems.

Diagnosis

DSG1 gene erythroderma is diagnosed through a combination of clinical examination, family history, and genetic testing. A skin biopsy may also be performed to confirm the diagnosis.

Genetic testing is the most reliable method of diagnosing DSG1 gene erythroderma. This involves sequencing the DSG1 gene to identify any mutations that may be causing the condition.

NGS Genetic DNA Test Cost

The cost of NGS genetic DNA testing for DSG1 gene erythroderma in India is approximately INR 20,000. This test is performed using next-generation sequencing technology, which allows for the simultaneous analysis of multiple genes.

NGS genetic DNA testing is a highly accurate method of diagnosing DSG1 gene erythroderma and can help guide treatment and management decisions for affected individuals and their families.

Conclusion

DSG1 gene erythroderma is a rare inherited skin disorder that can cause significant physical and emotional distress for affected individuals and their families. Early diagnosis and management are crucial for improving outcomes and quality of life. Genetic testing, including NGS genetic DNA testing, is an important tool for diagnosing DSG1 gene erythroderma and guiding treatment decisions.

If you suspect that you or a loved one may have DSG1 gene erythroderma, speak to a healthcare professional or genetic counselor to learn more about genetic testing options and treatment options.

At DNA Labs India, we offer a wide range of genetic testing services, including NGS genetic DNA testing for DSG1 gene erythroderma. Contact us today to learn more about our services and how we can help.