Short Description

NGS genetic DNA test detecets for variant and mutation detection in DRD4 gene for Attention deficit-hyperactivity disorder

PreTest Information

Clinical History of Patient who is going for DRD4 Gene Attention deficit-hyperactivity disorder NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with DRD4 Gene Attention deficit-hyperactivity disorder

Detail Description

DRD4 Gene and Attention Deficit-Hyperactivity Disorder: NGS Genetic DNA Test Cost INR 20,000

Attention Deficit-Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder affecting both children and adults. It is characterized by symptoms such as hyperactivity, impulsivity, and inattention. Although the exact causes of ADHD are not fully understood, recent studies have shown that genetics plays a significant role in the development of the disorder.

One of the genes that have been associated with ADHD is the DRD4 gene. The DRD4 gene codes for the dopamine receptor D4, which is involved in the regulation of dopamine levels in the brain. Dopamine is a neurotransmitter that plays a critical role in the reward and motivation systems of the brain, as well as in attention and learning.

Symptoms of ADHD

ADHD is typically diagnosed based on symptoms that persist for at least six months and are present in multiple settings, such as at home, school, or work. The symptoms of ADHD can be divided into three categories: inattention, hyperactivity, and impulsivity.

Some common symptoms of inattention include:

• Difficulty paying attention to details or making careless mistakes
• Difficulty staying focused on tasks or activities
• Difficulty organizing tasks and activities
• Forgetfulness and losing things frequently
• Avoiding tasks that require sustained mental effort

Some common symptoms of hyperactivity and impulsivity include:

• Fidgeting and squirming
• Leaving one's seat frequently
• Running or climbing excessively
• Talking excessively
• Interrupting others
• Difficulty waiting for one's turn

Diagnosis of ADHD

Diagnosing ADHD involves a comprehensive evaluation that includes a review of the patient's medical and family history, a physical exam, and a psychological evaluation. The evaluation may also involve interviews with family members, teachers, or coworkers to gather information about the patient's behavior in different settings.

There is no single test that can diagnose ADHD. However, healthcare professionals may use standardized rating scales to assess the severity of the patient's symptoms and determine whether they meet the criteria for a diagnosis of ADHD.

NGS Genetic DNA Test for DRD4 Gene and ADHD

Next-generation sequencing (NGS) is a powerful technology that can sequence large amounts of DNA quickly and accurately. With NGS, it is possible to sequence the entire DRD4 gene and identify any variations or mutations that may be associated with ADHD.

NGS genetic DNA tests for DRD4 gene and ADHD are available at DNA Labs India. The test involves collecting a small sample of the patient's DNA, which is then sequenced using NGS technology. The results of the test can provide valuable information about the patient's risk of developing ADHD and guide treatment decisions.

Cost of NGS Genetic DNA Test for DRD4 Gene and ADHD

The cost of the NGS genetic DNA test for DRD4 gene and ADHD at DNA Labs India is INR 20,000. The test is covered by most major health insurance plans and may be eligible for reimbursement through flexible spending accounts (FSAs) or health savings accounts (HSAs).

Conclusion

ADHD is a complex disorder that can have a significant impact on a patient's life. Understanding the genetic factors that contribute to the development of ADHD can help healthcare professionals develop more personalized treatment plans that address the unique needs of each patient. NGS genetic DNA tests for DRD4 gene and ADHD can provide valuable information that can guide diagnosis and treatment decisions.