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DNASE1L3 Gene Systemic lupus erythematosus type 16 NGS Genetic DNA Test Cost 20000 Rs
DNASE1L3 Gene Systemic lupus erythematosus type 16 NGS Genetic DNA Test Details
DNASE1L3 Gene Systemic lupus erythematosus type 16 NGS Genetic DNA Test cost INR:20000 symptoms diagnosis
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects various organs of the body. It is a complex disease that involves genetic, environmental, and hormonal factors. Researchers have identified many genes associated with SLE, including the DNASE1L3 gene, which is also known as systemic lupus erythematosus type 16.
What is the DNASE1L3 gene?
The DNASE1L3 gene is located on chromosome 3 and encodes an enzyme called deoxyribonuclease-1-like 3 (DNase-1L3). This enzyme is involved in the breakdown of DNA, which is necessary for the normal functioning of cells. However, in people with SLE, the DNASE1L3 gene may not function properly, leading to the accumulation of DNA fragments in the body and triggering an autoimmune response.
How is the DNASE1L3 gene related to SLE?
The DNASE1L3 gene is one of the many genes associated with SLE. Mutations in this gene have been found to increase the risk of developing SLE. In addition, some studies have shown that people with SLE have lower levels of DNase-1L3 enzyme activity, which may contribute to the pathogenesis of the disease.
What is an NGS Genetic DNA Test?
Next-generation sequencing (NGS) is a high-throughput DNA sequencing technology that enables the rapid and cost-effective analysis of large amounts of DNA. An NGS Genetic DNA Test can analyze multiple genes at once and identify genetic variations that may be associated with SLE. The test can be used to identify mutations in the DNASE1L3 gene, as well as other genes that may be involved in the development of SLE.
What are the symptoms of SLE?
SLE can affect multiple organs and can cause a wide range of symptoms, including:
- Fatigue
- Fever
- Joint pain and stiffness
- Rash
- Photosensitivity
- Mouth ulcers
- Kidney problems
- Lung problems
- Heart problems
How is SLE diagnosed?
SLE can be difficult to diagnose because the symptoms can vary widely and may mimic other diseases. The diagnosis is usually based on a combination of clinical symptoms, laboratory tests, and imaging studies. A doctor may order blood tests to check for antibodies and other markers of inflammation, as well as imaging studies to evaluate organ involvement.
What is the cost of an NGS Genetic DNA Test for SLE?
The cost of an NGS Genetic DNA Test for SLE can vary depending on the provider. At DNA Labs India, the cost of an NGS Genetic DNA Test for SLE is INR 20,000.
Conclusion
The DNASE1L3 gene is one of the many genes associated with SLE. Mutations in this gene have been found to increase the risk of developing SLE. An NGS Genetic DNA Test can be used to identify mutations in the DNASE1L3 gene, as well as other genes that may be involved in the development of SLE. If you are experiencing symptoms of SLE, it is important to speak with a healthcare provider to determine the best course of treatment.
