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Accurate Test Results for DNASE1 Gene Systemic lupus erythematosus NGS Genetic DNA Test
DNASE1 Gene Systemic lupus erythematosus NGS Genetic DNA Test Cost 20000 Rs
DNASE1 Gene Systemic lupus erythematosus NGS Genetic DNA Test Details
DNASE1 Gene and Systemic Lupus Erythematosus: NGS Genetic DNA Test Cost INR 20,000
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs in the body. It is characterized by the production of autoantibodies that attack the body's own tissues, leading to inflammation and damage. The exact cause of SLE is not known, but genetic factors play a significant role in its development. One of the genes that have been implicated in SLE is the DNASE1 gene.
What is the DNASE1 Gene?
The DNASE1 gene encodes an enzyme called deoxyribonuclease 1, which is responsible for breaking down DNA. This enzyme is important for the clearance of apoptotic cells, which are cells that have died naturally and need to be removed from the body. In people with SLE, there is a deficiency of DNASE1, which leads to the accumulation of apoptotic cells and the production of autoantibodies against them.
NGS Genetic DNA Test for DNASE1 Gene
The NGS Genetic DNA Test for the DNASE1 gene is a diagnostic tool that can identify mutations in the gene that may be associated with SLE. The test uses Next-Generation Sequencing (NGS) technology to analyze the entire DNASE1 gene and detect any variations in its sequence. The test is highly accurate and can detect even small changes in the gene that may be missed by other methods.
Cost of NGS Genetic DNA Test for DNASE1 Gene
The cost of the NGS Genetic DNA Test for the DNASE1 gene in India is approximately INR 20,000. The price may vary depending on the laboratory and the specific tests included in the package. However, it is important to note that this is a one-time investment that can provide valuable information about the risk of developing SLE.
Symptoms and Diagnosis of SLE
SLE can affect different parts of the body, and the symptoms may vary from person to person. Some common symptoms of SLE include:
- Joint pain and stiffness
- Fatigue
- Fever
- Rash on the face, neck, and chest
- Sensitivity to sunlight
- Mouth ulcers
- Swollen lymph nodes
Diagnosis of SLE involves a combination of clinical examination, laboratory tests, and imaging studies. The diagnosis is based on the presence of specific criteria, including:
- Malar rash
- Discoid rash
- Photosensitivity
- Oral ulcers
- Arthritis
- Serositis
- Renal disorder
- Neurological disorder
- Hematological disorder
- Immunological disorder
If you have any of the symptoms of SLE, it is important to consult a doctor and undergo a thorough evaluation. Early diagnosis and treatment can help manage the symptoms and prevent complications.
Conclusion
The DNASE1 gene is one of the genes that have been implicated in the development of SLE. The NGS Genetic DNA Test for the DNASE1 gene is a valuable diagnostic tool that can identify mutations in the gene that may be associated with SLE. The cost of the test in India is INR 20,000, which is a one-time investment that can provide valuable information about the risk of developing SLE. If you have any symptoms of SLE, it is important to consult a doctor and undergo a thorough evaluation.
