Short Description

NGS genetic DNA test detecets for variant and mutation detection in DMD gene for Muscular dystrophy, Becker type

PreTest Information

Clinical History of Patient who is going for DMD Gene Muscular dystrophy, Becker type NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with DMD Gene Muscular dystrophy, Becker type

Detail Description

DMD Gene Muscular Dystrophy, Becker Type - NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

Muscular dystrophy is a group of inherited disorders that cause progressive muscle weakness and wasting. One of the most common types of muscular dystrophy is Duchenne muscular dystrophy (DMD). DMD is caused by mutations in the DMD gene, which encodes the protein dystrophin. This protein is essential for maintaining the structure and function of muscle fibers. Without dystrophin, the muscles become weak and eventually degenerate.

Symptoms of DMD Becker Type

The symptoms of DMD usually start to appear in early childhood, typically between the ages of 3 and 5 years. Children with DMD may have difficulty walking, running, and climbing stairs. They may also have trouble getting up from a sitting or lying position. As the disease progresses, the muscles of the arms, legs, and trunk become weaker and the child may develop scoliosis (curvature of the spine).

Becker muscular dystrophy (BMD) is a milder form of DMD. It is caused by mutations in the same gene but the mutations are different. People with BMD usually have a later onset of symptoms, typically in their teenage years or later. The progression of the disease is slower than in DMD, and many people with BMD are able to walk into adulthood. However, they may still experience muscle weakness and wasting.

Diagnosis of DMD Becker Type

The diagnosis of DMD or BMD is usually made based on clinical symptoms and family history. A genetic test can confirm the diagnosis and determine the specific mutation in the DMD gene. Next-generation sequencing (NGS) is a powerful tool for genetic testing that can detect mutations in multiple genes simultaneously. NGS can be used to diagnose DMD or BMD and to identify carriers of the disease.

NGS Genetic DNA Test Cost INR:20000

The cost of an NGS genetic DNA test for DMD or BMD in India is around INR 20000. The cost may vary depending on the laboratory and the specific test ordered. It is important to choose a reputable laboratory with experience in genetic testing and counseling.

Conclusion

DMD and BMD are genetic disorders that cause progressive muscle weakness and wasting. Early diagnosis is important for managing the symptoms and planning appropriate treatment. NGS genetic DNA testing can confirm the diagnosis and identify carriers of the disease. The cost of NGS genetic DNA testing in India is around INR 20000. If you or someone you know is experiencing symptoms of muscular dystrophy, it is important to consult a healthcare professional and consider genetic testing.

For reliable and accurate genetic testing, DNA Labs India is a trusted laboratory with expertise in genetic testing and counseling. Contact us today for more information.

Becker muscular dystrophy (BMD) is a genetic disorder that primarily affects muscles, leading to muscle weakness and wasting. It is caused by mutations in the DMD gene, which encodes the protein dystrophin. BMD is related to Duchenne muscular dystrophy (DMD), but it is generally less severe and has a later onset.

The DMD gene is responsible for producing the dystrophin protein, which plays a crucial role in maintaining the structure and function of muscle cells. Mutations in the DMD gene can result in a deficiency or abnormality of dystrophin, leading to muscle degeneration.

An NGS (Next-Generation Sequencing) Genetic DNA Test can analyze the DMD gene for mutations that are associated with Becker muscular dystrophy. Identifying these mutations can help with the diagnosis and management of the condition.

Individuals with Becker muscular dystrophy may experience progressive muscle weakness and difficulty with mobility. Symptoms usually appear later in childhood or adolescence compared to the earlier onset of symptoms in Duchenne muscular dystrophy.

If you suspect that you or someone you know might have Becker muscular dystrophy or if there is a family history of the condition, consulting with a neurologist, a medical geneticist, or a genetic counselor is advisable. They can guide you through the process of genetic testing, explain the implications of the results, and provide information about the condition, management, and support resources. Keep in mind that genetic testing results are best interpreted in consultation with qualified healthcare professionals.