Short Description

NGS genetic DNA test detecets for variant and mutation detection in DCX gene for Lissencephaly/Subcortical laminal heteropia, X-linked

PreTest Information

Clinical History of Patient who is going for DCX Gene Lissencephaly/Subcortical laminal heteropia, X-linked NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with DCX Gene Lissencephaly/Subcortical laminal heteropia, X-linked

Detail Description

Understanding DCX Gene Lissencephaly/Subcortical Laminal Heteropia and X-Linked NGS Genetic DNA Test Cost in India

DCX gene lissencephaly/subcortical laminal heteropia is a rare genetic disorder that affects brain development. It is caused by mutations in the DCX gene, which plays a critical role in the migration of neurons during fetal brain development. As a result, individuals with this disorder have abnormal brain structures, including a smooth brain surface, and subcortical bands or nodular masses in the white matter of the brain.

The disorder can affect males and females, but it is more common in males. The symptoms of DCX gene lissencephaly/subcortical laminal heteropia can vary widely depending on the severity of the condition. Some individuals may have mild symptoms, while others may have severe intellectual disability, seizures, and difficulty with movement.

Diagnosis

Diagnosing DCX gene lissencephaly/subcortical laminal heteropia can be challenging because the symptoms can vary widely. A diagnosis is typically made based on a combination of clinical evaluation, imaging studies, and genetic testing.

Imaging studies such as magnetic resonance imaging (MRI) can help identify abnormal brain structures, including a smooth brain surface and subcortical bands or nodular masses in the white matter of the brain. Genetic testing can confirm the presence of mutations in the DCX gene.

NGS Genetic DNA Test

NGS Genetic DNA Test is a next-generation sequencing technology that enables the rapid and cost-effective analysis of genetic mutations. It is a powerful tool for diagnosing genetic disorders, including DCX gene lissencephaly/subcortical laminal heteropia.

The NGS Genetic DNA Test can analyze multiple genes simultaneously, which makes it an efficient way to identify mutations in the DCX gene. The test involves collecting a small sample of blood or tissue from the patient and analyzing the DNA for mutations in the DCX gene.

Cost

The cost of NGS Genetic DNA Test for DCX gene lissencephaly/subcortical laminal heteropia in India can vary depending on the laboratory and the specific test being performed. On average, the cost of the test ranges from INR 15,000 to INR 25,000.

However, it is important to note that the cost of the test may not be covered by insurance, and patients should check with their insurance provider to determine coverage.

Conclusion

DCX gene lissencephaly/subcortical laminal heteropia is a rare genetic disorder that can have significant impacts on brain development and function. A timely and accurate diagnosis is critical for managing the symptoms of the disorder and providing appropriate treatment.

NGS Genetic DNA Test is a powerful tool for diagnosing genetic disorders, including DCX gene lissencephaly/subcortical laminal heteropia. Patients should consult with their healthcare provider to determine if this test is appropriate for their situation and to discuss the cost and insurance coverage.