Short Description

NGS genetic DNA test detecets for variant and mutation detection in DAG1 gene for Muscular dystrophy-dystroglycanopathy (limb-girdle), type C9

PreTest Information

Clinical History of Patient who is going for DAG1 Gene Muscular dystrophy-dystroglycanopathy (limb-girdle), type C9 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with DAG1 Gene Muscular dystrophy-dystroglycanopathy (limb-girdle), type C9

Detail Description

DNA Labs India - DAG1 Gene Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C9 NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

At DNA Labs India, we offer a wide range of DNA testing services, including the DAG1 gene muscular dystrophy-dystroglycanopathy (limb-girdle), type C9 NGS genetic DNA test. This test is designed to identify the presence of mutations in the DAG1 gene, which can cause limb-girdle muscular dystrophy-dystroglycanopathy.

Symptoms of DAG1 Gene Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C9

The symptoms of limb-girdle muscular dystrophy-dystroglycanopathy can vary widely from person to person. Some of the most common symptoms include:

• Muscle weakness and wasting in the hips and shoulders
• Difficulty walking and running
• Frequent falls
• Difficulty climbing stairs or standing up from a seated position
• Reduced ability to raise the arms above the head
• Contractures (permanent muscle shortening) in the elbows and ankles
• Respiratory problems (in severe cases)

Diagnosis of DAG1 Gene Muscular Dystrophy-Dystroglycanopathy (Limb-Girdle), Type C9

Diagnosis of limb-girdle muscular dystrophy-dystroglycanopathy typically involves a combination of physical exams, medical history reviews, and diagnostic tests. Some of the most common tests used to diagnose the condition include:

• Blood tests to look for elevated levels of creatine kinase (a muscle enzyme)
• Muscle biopsies to examine the muscle tissue for abnormalities
• Genetic testing to identify mutations in the DAG1 gene
• Electromyography (EMG) to measure muscle activity
• Nerve conduction studies to measure the speed at which nerves send electrical signals

NGS Genetic DNA Test Cost

At DNA Labs India, we offer the DAG1 gene muscular dystrophy-dystroglycanopathy (limb-girdle), type C9 NGS genetic DNA test at an affordable cost of INR 20000. Our test is accurate, reliable, and provides quick results.

If you suspect that you or a loved one may be affected by limb-girdle muscular dystrophy-dystroglycanopathy, it is important to seek medical attention right away. Contact DNA Labs India today to learn more about our DAG1 gene muscular dystrophy-dystroglycanopathy (limb-girdle), type C9 NGS genetic DNA test and how it can help diagnose this condition.

The DAG1 gene is associated with a group of genetic disorders known as muscular dystrophy-dystroglycanopathies (MDDGs), specifically a subtype referred to as limb-girdle muscular dystrophy-dystroglycanopathy type C9 (LGMD-DGC9). These are a group of rare inherited muscle disorders characterized by progressive muscle weakness and wasting due to abnormalities in the dystroglycan complex, a group of proteins critical for maintaining the structural integrity of muscle tissues.

NGS (Next-Generation Sequencing) Genetic DNA Testing is a technique used to analyze multiple genes simultaneously to identify genetic mutations or variations associated with specific conditions. In the context of LGMD-DGC9, NGS testing can help identify mutations in the DAG1 gene that are responsible for the disorder.

Symptoms of LGMD-DGC9 can include muscle weakness, difficulty walking, running, and climbing stairs, as well as potential respiratory and cardiac complications. The severity of symptoms can vary widely among affected individuals.

Genetic testing, including NGS-based testing, plays a crucial role in diagnosing genetic disorders like LGMD-DGC9. Identifying the specific genetic mutations responsible for the disorder can help with accurate diagnosis, understanding disease progression, and providing appropriate medical management and counseling.

If you or someone you know is suspected of having LGMD-DGC9 or any other genetic disorder, it's important to consult a medical geneticist, genetic counselor, or healthcare provider who specializes in genetics. They can guide you through the process of genetic testing, explain the results, and provide information about available treatments or interventions.