Short Description

NGS genetic DNA test detecets for variant and mutation detection in CYP3A5 gene for Hypertension, salt-sensitive essential, susceptibility to

PreTest Information

Clinical History of Patient who is going for CYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CYP3A5 Gene Hypertension, salt-sensitive essential, susceptibility to NGS Genetic DNA Test gene CYP3A5

Detail Description

CYP3A5 Gene Hypertension: Understanding Salt-Sensitive Essential and Susceptibility to NGS Genetic DNA Test

High blood pressure or hypertension is a chronic condition that affects millions of people worldwide. It is a leading cause of heart disease, stroke, and other health complications. While several factors contribute to hypertension, genetics is one of the significant factors. Several genes have been associated with hypertension, and the CYP3A5 gene is one of them.

Understanding CYP3A5 Gene Hypertension

The CYP3A5 gene produces an enzyme that helps in the metabolism of drugs and other foreign substances in the body. It also plays a crucial role in the regulation of blood pressure. Studies have shown that variations in the CYP3A5 gene are associated with salt-sensitive hypertension, which is a particular type of essential hypertension.

Salt-sensitive hypertension is a condition where blood pressure increases in response to high levels of salt in the diet. It is estimated that about 50% of individuals with essential hypertension have salt-sensitive hypertension. This type of hypertension is prevalent in people of African or Hispanic descent.

Symptoms of CYP3A5 Gene Hypertension

High blood pressure often has no symptoms, which is why it is referred to as the "silent killer." However, some people with hypertension may experience symptoms such as:

• Headaches
• Dizziness
• Nosebleeds
• Shortness of breath
• Chest pain
• Irregular heartbeat

It is essential to get regular blood pressure checks to detect hypertension early. Early detection can help prevent complications such as heart disease, stroke, and kidney damage.

Diagnosis of CYP3A5 Gene Hypertension

Diagnosis of hypertension is done through blood pressure measurement. A blood pressure reading of 130/80 mm Hg or higher is considered high. Further testing may be done to identify the underlying cause of hypertension, such as genetic testing.

NGS Genetic DNA test is a type of genetic testing that can identify variations in the CYP3A5 gene. This test can help determine if a person is susceptible to salt-sensitive hypertension and provide early intervention to prevent complications. The cost of the NGS Genetic DNA test is INR 20,000.

Conclusion

CYP3A5 Gene Hypertension is a significant contributor to essential hypertension, particularly salt-sensitive hypertension. Regular blood pressure checks and early detection through genetic testing can help prevent complications. DNA Labs India offers NGS Genetic DNA testing for CYP3A5 Gene Hypertension at an affordable cost of INR 20,000. Contact us today to schedule your test and take control of your health.

Salt-sensitive essential hypertension refers to a type of high blood pressure that is particularly responsive to changes in salt (sodium) intake. It's believed that genetic factors play a role in determining an individual's susceptibility to salt-sensitive hypertension. One of the genes that has been studied in this context is the CYP3A5 gene.