Short Description

Genetic polymorphism (mainly CYP2C19*2, CYP2C19*3 and CYP2C19*17) exists for CYP2C19 expression, with approximately 3ƒ??5% of Caucasian and 15ƒ??20% of Asian populations being poor metabolizers with no CYP2C19 function. This may reduce the efficacy of Clopidogrel (Plavix). In patients with an abnormal CYP2C19 variant certain Benzodiazepines should be avoided, such as Diazepam (Valium), Lorazepam (Ativan), Oxazepam (Serax), and Temazepam (Restoril).

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

CYP2C19 Genotyping Test: Cost, Symptoms, and Diagnosis

Genetics has a significant role to play in determining how an individual responds to drugs. The CYP2C19 gene is responsible for a specific enzyme in the liver that plays a crucial role in metabolizing drugs. CYP2C19 genotyping test helps in identifying the genetic variations in this gene that can affect an individual's drug response. DNA Labs India offers CYP2C19 genotyping test at an affordable cost of INR 10,500. Let's understand the symptoms, diagnosis, and cost of the CYP2C19 genotyping test in detail.

Symptoms of CYP2C19 Gene Variations

CYP2C19 gene variations can lead to altered drug metabolism, which can result in drug toxicity or reduced efficacy. Some of the symptoms that individuals with CYP2C19 gene variations may experience are:

• Abdominal pain
• Headache
• Dizziness
• Nausea and vomiting
• Unexplained fever
• Skin rashes
• Difficulty breathing

If you experience any of these symptoms after taking medication, it is advisable to consult a doctor who may recommend a CYP2C19 genotyping test.

Diagnosis of CYP2C19 Gene Variations

The CYP2C19 genotyping test is a simple blood test that helps in identifying genetic variations in the CYP2C19 gene. The test analyzes the DNA samples to determine the patient's genotype, which can be classified into three categories:

• Extensive metabolizers (EM) - have normal CYP2C19 function
• Intermediate metabolizers (IM) - have reduced CYP2C19 function
• Poor metabolizers (PM) - have no CYP2C19 function

The test results help in identifying which medications are safe and effective for the patient, and which ones should be avoided or prescribed at a lower dose.

Cost of CYP2C19 Genotyping Test

DNA Labs India offers CYP2C19 genotyping test at an affordable cost of INR 10,500. The test is conducted using state-of-the-art technology and is performed by highly skilled professionals. The test results are accurate and reliable, helping physicians make informed decisions about the patient's drug therapy.

Conclusion

The CYP2C19 genotyping test is a valuable tool that helps in identifying genetic variations that can affect an individual's drug response. DNA Labs India offers the test at an affordable cost of INR 10,500. If you experience any symptoms after taking medication, it is advisable to consult a doctor who may recommend the CYP2C19 genotyping test. The test results can help in identifying which medications are safe and effective for the patient, and which ones should be avoided or prescribed at a lower dose.

For more information about the CYP2C19 genotyping test, contact DNA Labs India today!