Short Description

Cryoglobulins are proteins that precipitate spontaneously and reversibly at less than body temperature within 3 days. They are insoluble at 4?øC and may aggregate upto 30?øC. They have a tendency to fix complement and initiate inflammatory reaction. This assay is useful for evaluating patients with Vasculitis, Glomerulonephritis and Lymphoproliferative disease. It also helps to evaluate patients with Macroglobulinemia and Myeloma who are symptomatic on exposure to cold.

PreTest Information

No special preparation required

Detail Description

CRYOGLOBULINS QUALITATIVE Test: Cost, Symptoms, and Diagnosis

Cryoglobulins are proteins that become insoluble at low temperatures, forming clumps that can block blood vessels and cause a range of symptoms. The Cryoglobulins Qualitative Test is a diagnostic tool that can be used to detect the presence of cryoglobulins in the blood. In this blog post, we will discuss the cost of the test, symptoms of cryoglobulinemia, and how the diagnosis is made.

Cost of Cryoglobulins Qualitative Test in India

The cost of the Cryoglobulins Qualitative Test in India varies from one laboratory to another. On average, the cost of the test ranges from INR 1000 to INR 1500. DNA Labs India is a leading provider of diagnostic services in India that offers the Cryoglobulins Qualitative Test at a cost of INR 1111.5.

Symptoms of Cryoglobulinemia

The symptoms of cryoglobulinemia can vary widely depending on the severity of the condition. Some of the common symptoms include:

• Joint pain and stiffness
• Purplish skin rash on the legs and arms
• Numbness or tingling in the hands and feet
• Weakness and fatigue
• Abdominal pain and bloating
• Swelling in the legs and feet
• Shortness of breath
• High blood pressure

It is important to note that not everyone with cryoglobulinemia will experience all of these symptoms. Some people may have only one or two of these symptoms, while others may have no symptoms at all.

Diagnosis of Cryoglobulinemia

The diagnosis of cryoglobulinemia is made through a combination of medical history, physical examination, and laboratory tests. The Cryoglobulins Qualitative Test is one of the tests that can be used to diagnose the condition.

If cryoglobulinemia is suspected, the doctor may order a series of blood tests. These tests may include:

• Complete blood count (CBC)
• Kidney function tests
• Liver function tests
• C-reactive protein (CRP) test
• Rheumatoid factor (RF) test
• Cryoglobulins Qualitative Test

Additional tests may be needed to determine the underlying cause of cryoglobulinemia.

Conclusion

The Cryoglobulins Qualitative Test is a valuable tool in the diagnosis of cryoglobulinemia, a condition that can cause a range of symptoms. DNA Labs India offers the test at a cost of INR 1111.5. If you are experiencing any of the symptoms associated with cryoglobulinemia, it is important to speak with your doctor to determine the underlying cause and get appropriate treatment.

For more information on the Cryoglobulins Qualitative Test, visit the DNA Labs India website today.

Cold Precipitation: The separated serum is cooled gradually to a low temperature, usually around 4°C (39°F), to see if any precipitates or gel-like structures form. Cryoglobulins are only detected if they precipitate or gel at this temperature.

1. Visual Inspection: The serum is examined for the presence of precipitates or gel-like structures. If these structures are observed, it indicates the presence of cryoglobulins.

2. Results: The test provides a qualitative result indicating either "positive" (cryoglobulins are present) or "negative" (cryoglobulins are not present).

If the qualitative cryoglobulins test is positive, further testing may be required to quantify the levels of cryoglobulins and identify any underlying conditions or causes associated with cryoglobulinemia. Cryoglobulinemia can be linked to autoimmune disorders, chronic infections (such as hepatitis C), and certain cancers.

It's important to note that the qualitative test provides information about the presence or absence of cryoglobulins, but it doesn't provide information about the specific type or quantity of cryoglobulins present. Therefore, in cases where cryoglobulinemia is suspected, additional tests and clinical evaluation are usually needed for a comprehensive diagnosis and treatment plan.

If you or someone you know is suspected of having cryoglobulinemia or related symptoms, a healthcare provider will order this test. The results, along with other clinical information and additional tests, will help in diagnosing the condition and planning appropriate management strategies. Always consult a healthcare professional for proper evaluation and interpretation of test results.