Short Description

Direct Coombs test detects IgG and Complement bound to erythrocytes. The test is useful in diagnosing patients with Hemolytic disease of the newborn and Autoimmune Hemolytic Anemia. Drug induced antibodies may give false positive reactions.

PreTest Information

No special preparation required

Detail Description

COOMBS TEST DIRECT: Symptoms, Diagnosis, and Cost in India

Are you experiencing symptoms such as fatigue, weakness, and pale skin? These could be signs of hemolytic anemia, a condition where your body destroys red blood cells faster than it can produce them. One test that can help diagnose this condition is the Coombs test direct.

What is the Coombs test direct?

The Coombs test direct, also known as the direct antiglobulin test (DAT), is a blood test that detects antibodies or complement proteins attached to the surface of red blood cells. These antibodies or proteins can cause the destruction of red blood cells, leading to anemia.

The test is commonly used to diagnose autoimmune hemolytic anemia, a type of hemolytic anemia where the body's immune system mistakenly attacks its own red blood cells. It can also be used to diagnose hemolytic disease of the newborn, a condition where a mother's antibodies attack her baby's red blood cells.

How is the Coombs test direct performed?

The Coombs test direct is a simple blood test that can be done in a laboratory or a hospital. A small sample of blood is taken from a vein in your arm and sent to a lab for analysis. The sample is mixed with a special reagent that binds to any antibodies or complement proteins attached to red blood cells. If the reagent binds to the red blood cells, it indicates a positive result for the Coombs test direct.

What are the symptoms of hemolytic anemia?

The symptoms of hemolytic anemia can vary depending on the severity of the condition. Common symptoms include:

• Fatigue
• Weakness
• Pale skin
• Shortness of breath
• Rapid heartbeat
• Yellowing of the skin and eyes (jaundice)

If you are experiencing any of these symptoms, it is important to see a doctor for a proper diagnosis and treatment.

What is the cost of the Coombs test direct in India?

The cost of the Coombs test direct in India can vary depending on the location and the lab where the test is performed. On average, the cost of the test ranges from INR 500 to INR 800. At DNA Labs India, the cost of the Coombs test direct is INR 549.9.

Conclusion

The Coombs test direct is an important blood test that can help diagnose hemolytic anemia, a condition where the body destroys red blood cells faster than it can produce them. If you are experiencing symptoms such as fatigue, weakness, and pale skin, it is important to see a doctor for a proper diagnosis and treatment. At DNA Labs India, we offer the Coombs test direct at an affordable cost of INR 549.9. Contact us today to schedule an appointment.