Short Description

NGS genetic DNA test detecets for variant and mutation detection in CLCN5 gene for Dent disease

PreTest Information

Clinical History of Patient who is going for CLCN5 Gene Dent disease NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CLCN5 Gene Dent disease NGS Genetic DNA Test gene CLCN5

Detail Description

CLCN5 Gene Dent disease NGS Genetic DNA Test: Symptoms, Diagnosis and Cost

Dent disease is a rare genetic disorder that primarily affects males. It is caused by mutations in the CLCN5 gene which plays a crucial role in regulating the amount of calcium and other ions in the kidney. This disorder is characterized by the progressive damage of the kidneys, leading to impaired kidney function and the formation of kidney stones. The symptoms of Dent disease may appear in childhood and can worsen over time. If you suspect you or a loved one may have Dent disease, it is important to seek medical attention and consider genetic testing.

Symptoms of Dent Disease

The symptoms of Dent disease may vary from person to person and can include:

• Frequent urination
• Painful urination
• Blood in the urine
• Kidney stones
• Weakness and fatigue
• Difficulty concentrating

Some people with Dent disease may also develop chronic kidney disease, which can lead to kidney failure.

Diagnosis of Dent Disease

To diagnose Dent disease, your doctor will first perform a physical exam and take a medical history. They may also order blood and urine tests to check kidney function and look for signs of kidney damage. If Dent disease is suspected, genetic testing can be done to confirm the diagnosis. Next-generation sequencing (NGS) is a powerful tool that can analyze multiple genes at once, including the CLCN5 gene. NGS can provide a more comprehensive understanding of the genetic mutations that may be causing Dent disease.

Cost of Dent Disease NGS Genetic DNA Test

The cost of the Dent disease NGS genetic DNA test in India can vary depending on the laboratory and the specific testing procedure used. On average, the cost of the test is around INR 20,000. However, some insurance plans may cover the cost of genetic testing. It is important to check with your insurance provider to see if genetic testing is covered under your policy.

Conclusion

Dent disease is a rare genetic disorder that can have serious consequences if left untreated. If you or a loved one are experiencing symptoms of Dent disease, it is important to seek medical attention and consider genetic testing. The CLCN5 gene Dent disease NGS genetic DNA test can help confirm a diagnosis and provide valuable information for treatment and management of the disorder. With advances in genetic testing technology, the cost of testing has become more affordable, making it accessible to more people who may need it.

At DNA Labs India, we offer a range of genetic testing services, including the Dent disease NGS genetic DNA test. Our team of genetic counselors and scientists are dedicated to providing accurate and reliable testing results to help improve the health and well-being of our patients. Contact us today to learn more about our genetic testing services.