Short Description

Chronic Lymphocytic Leukemia (CLL) results in the progressive accumulation of CD5(+) CD23(+) B lymphocytes that appear morphologically mature but are functionally incompetent in bone marrow, blood, spleen and lymph nodes of the affected person. Chromosomal translocations are rare events in B-CLL, whereas copy number changes of certain chromosomal regions are frequent, and some of these have been found to be highly prognostic markers of CLL.

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

Chronic Lymphocytic Leukemia (CLL) Mutations Detection Comprehensive Panel Test

Chronic Lymphocytic Leukemia (CLL) is a type of cancer that affects the blood and bone marrow. It is a slow-growing cancer that develops in the white blood cells called lymphocytes. CLL is the most common type of leukemia in adults and is most common in people over 60 years old.

CLL can be caused by mutations in the DNA of the cells that make up the lymphatic system. These mutations can cause the cells to grow and divide uncontrollably, leading to the development of cancer. The DNA Labs India offers a comprehensive panel test that can detect mutations associated with CLL.

Symptoms of CLL

The symptoms of CLL can vary from person to person. Some people may experience no symptoms at all, while others may experience:

• Fatigue
• Night sweats
• Enlarged lymph nodes
• Weight loss
• Frequent infections
• Easy bruising or bleeding

Many of these symptoms can also be caused by other conditions, so it is important to consult a doctor if you are experiencing any of these symptoms.

Diagnosis of CLL

CLL is usually diagnosed through a combination of physical examination, blood tests, and bone marrow biopsy. During a physical examination, the doctor will look for signs of enlarged lymph nodes or an enlarged spleen. Blood tests can help to identify abnormal lymphocytes and other markers that may indicate CLL. A bone marrow biopsy can help to confirm the diagnosis and determine the extent of the disease.

CLL Mutations Detection Comprehensive Panel Test

The DNA Labs India offers a comprehensive panel test that can detect mutations associated with CLL. This test uses advanced sequencing technology to analyze the DNA of the cells that make up the lymphatic system. The test can identify mutations in genes such as TP53, ATM, NOTCH1, SF3B1, and others that are commonly associated with CLL.

The test is simple and non-invasive. A small blood sample is taken, and the DNA is extracted and analyzed. The results of the test can help doctors to better understand the extent of the disease and develop a personalized treatment plan.

Test Cost

The cost of the CLL Mutations Detection Comprehensive Panel Test at DNA Labs India is INR 9000. The test is covered by most insurance plans, and financial assistance may be available for those who qualify.

Conclusion

CLL is a type of cancer that affects the blood and bone marrow. It can be caused by mutations in the DNA of the cells that make up the lymphatic system. The DNA Labs India offers a comprehensive panel test that can detect mutations associated with CLL. The test is simple, non-invasive, and can help doctors to better understand the extent of the disease and develop a personalized treatment plan.

If you are experiencing symptoms of CLL or have been diagnosed with the disease, it is important to consult a doctor and consider the CLL Mutations Detection Comprehensive Panel Test offered by DNA Labs India.