Short Description

NGS genetic DNA test detecets for variant and mutation detection in CFTR gene for Cystic fibrosis

PreTest Information

Clinical History of Patient who is going for CFTR Gene Cystic fibrosis NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Cystic fibrosis

Detail Description

CFTR Gene and Cystic Fibrosis: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

Cystic fibrosis (CF) is a genetic disorder that affects the respiratory, digestive, and reproductive systems. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which is responsible for producing a protein that regulates the movement of salt and water in and out of cells.

CF is a progressive disease that can cause a range of symptoms, including:

• Chronic coughing, wheezing, and shortness of breath
• Frequent lung infections
• Poor growth and weight gain
• Malabsorption of nutrients
• Infertility in males

The severity of CF symptoms can vary widely from person to person, depending on the specific CFTR gene mutations they inherit.

Diagnosis of CF

CF is usually diagnosed through a combination of physical exams, medical history, and genetic testing. A sweat test is often used to confirm a diagnosis, as people with CF have higher levels of salt in their sweat.

Genetic testing can also be used to identify CFTR gene mutations. Next-generation sequencing (NGS) is a type of genetic testing that can sequence multiple genes at once, making it a powerful tool for identifying the specific mutations causing CF.

NGS Genetic DNA Test Cost in India

In India, the cost of NGS genetic testing for CF can vary depending on the specific test and the laboratory performing it. On average, NGS genetic testing for CF can cost around INR 20,000.

While this may seem expensive, genetic testing can provide valuable information about an individual's risk for CF and help guide treatment decisions. It can also provide information about the risk of passing CF on to future children.

Conclusion

Cystic fibrosis is a serious genetic disorder that can have a significant impact on an individual's health and quality of life. While there is no cure for CF, early diagnosis and treatment can help manage symptoms and improve outcomes.

NGS genetic testing can play an important role in diagnosing CF and identifying the specific mutations causing the disease. While the cost of genetic testing may be a barrier for some, it is an investment in better health outcomes and can provide valuable information for individuals and families affected by CF.

For those concerned about the possibility of CF, DNA Labs India offers a range of genetic testing services, including NGS genetic testing for CF. Contact us today to learn more.