Short Description

NGS genetic DNA test detecets for variant and mutation detection in CD59 gene for Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy

PreTest Information

Clinical History of Patient who is going for CD59 Gene Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CD59 Gene Hemolytic anemia, CD59-mediated, with or without immune-mediated polyneuropathy NGS Genetic DNA Test gene CD59

Detail Description

CD59 Gene Hemolytic Anemia and CD59-mediated Immune-Mediated Polyneuropathy: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Hemolytic anemia is a medical condition in which the red blood cells are destroyed faster than they are produced. This condition can be caused by a variety of factors, including genetic mutations. One such genetic mutation is related to the CD59 gene, which plays a crucial role in protecting red blood cells from destruction by the immune system.

In some cases, CD59 gene mutations can lead to CD59-mediated hemolytic anemia, a condition in which the immune system attacks and destroys red blood cells. This condition can also be accompanied by immune-mediated polyneuropathy, a disorder that affects the nerves outside of the brain and spinal cord.

Symptoms of CD59-mediated Hemolytic Anemia and Polyneuropathy

The symptoms of CD59-mediated hemolytic anemia and polyneuropathy can vary depending on the severity of the condition. Some common symptoms of hemolytic anemia include:

• Fatigue and weakness
• Shortness of breath
• Pale skin
• Jaundice (yellowing of the skin and eyes)
• Dark urine
• Enlarged spleen

On the other hand, the symptoms of immune-mediated polyneuropathy may include:

• Tingling or numbness in the hands and feet
• Muscle weakness
• Difficulty walking or performing fine motor tasks
• Loss of reflexes
• Pain or cramping in the muscles

Diagnosis of CD59-mediated Hemolytic Anemia and Polyneuropathy

The diagnosis of CD59-mediated hemolytic anemia and polyneuropathy typically involves a combination of physical exams, blood tests, and nerve conduction studies. A doctor may also order additional tests such as a bone marrow biopsy or genetic testing to confirm a diagnosis.

NGS Genetic DNA Test Cost

NGS Genetic DNA testing is a type of genetic testing that can identify mutations in the CD59 gene that may lead to hemolytic anemia and polyneuropathy. This test typically costs around INR 20,000 in India.

Conclusion

CD59-mediated hemolytic anemia and polyneuropathy can be a debilitating condition that affects many people around the world. However, with early diagnosis and treatment, patients can manage their symptoms and improve their quality of life. If you suspect that you or a loved one may have this condition, it is important to seek medical attention from a qualified healthcare provider.