Short Description

NGS genetic DNA test detecets for variant and mutation detection in CBLIF gene for Intrinsic factor deficiency

PreTest Information

Clinical History of Patient who is going for CBLIF Gene Intrinsic factor deficiency NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CBLIF Gene Intrinsic factor deficiency NGS Genetic DNA Test gene CBLIF

Detail Description

CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test

Are you experiencing symptoms of vitamin B12 deficiency such as fatigue, weakness, numbness, or tingling? Have you been diagnosed with pernicious anemia or other conditions that affect your body’s ability to absorb vitamin B12? If so, you may have a genetic mutation in the CBLIF gene that is contributing to your condition. A CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test can help diagnose this condition and provide valuable information for treatment.

What is the CBLIF gene?

The CBLIF gene is responsible for producing a protein known as intrinsic factor. Intrinsic factor is essential for the absorption of vitamin B12 in the small intestine. Without intrinsic factor, the body cannot absorb vitamin B12 from food or supplements, leading to a deficiency. This deficiency can cause a range of symptoms and health problems if left untreated.

What is intrinsic factor deficiency?

Intrinsic factor deficiency occurs when the body cannot produce enough intrinsic factor to absorb vitamin B12. This can be caused by a genetic mutation in the CBLIF gene or by other conditions that affect the production or function of intrinsic factor. Intrinsic factor deficiency can lead to pernicious anemia, a condition characterized by low red blood cell counts, fatigue, weakness, and other symptoms.

What is a CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test?

A CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test is a genetic test that can identify mutations in the CBLIF gene that may be contributing to intrinsic factor deficiency. This test uses next-generation sequencing (NGS) technology to analyze your DNA and look for specific mutations in the CBLIF gene. This test can also identify other genetic mutations that may be contributing to your condition.

What are the symptoms of intrinsic factor deficiency?

The symptoms of intrinsic factor deficiency can vary depending on the severity of the condition. Common symptoms include:

• Fatigue
• Weakness
• Numbness or tingling in the hands and feet
• Difficulty walking
• Loss of appetite
• Weight loss
• Depression
• Irritability
• Memory loss

How is intrinsic factor deficiency diagnosed?

Intrinsic factor deficiency is typically diagnosed through a blood test that measures the levels of vitamin B12 and other markers in the blood. If intrinsic factor deficiency is suspected, your doctor may also perform a test to measure the levels of intrinsic factor in your blood. A CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test can also help diagnose this condition by identifying genetic mutations that may be contributing to your symptoms.

What is the cost of a CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test?

The cost of a CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test can vary depending on the laboratory and the specific tests performed. At DNA Labs India, we offer this test for a cost of INR 20,000. This test includes a comprehensive analysis of your DNA to identify mutations in the CBLIF gene and other genetic factors that may be contributing to your condition.

Conclusion

A CBLIF Gene Intrinsic Factor Deficiency NGS Genetic DNA Test can provide valuable information for the diagnosis and treatment of intrinsic factor deficiency. If you are experiencing symptoms of vitamin B12 deficiency or have been diagnosed with pernicious anemia, this test may be a useful tool for understanding the underlying genetic factors contributing to your condition. At DNA Labs India, we offer comprehensive genetic testing services to help you take control of your health.

It seems there might be a misunderstanding or typo in the gene name "CBLIF." As of my last update in September 2021, there is no gene known as CBLIF associated with intrinsic factor deficiency. Intrinsic factor deficiency is typically related to mutations in the GIF gene, which encodes for gastric intrinsic factor.