Short Description

NGS genetic DNA test detecets for variant and mutation detection in CBL gene for Juvenile myelomonocytic leukemia, due to CBL germline mutation

PreTest Information

Clinical History of Patient who is going for CBL Gene Juvenile myelomonocytic leukemia, due to CBL germline mutation NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CBL Gene Juvenile myelomonocytic leukemia, due to CBL germline mutation NGS Genetic DNA Test gene CBL

Detail Description

CBL Gene Juvenile Myelomonocytic Leukemia

Juvenile myelomonocytic leukemia (JMML) is a rare blood cancer that affects children. It is characterized by the overproduction of white blood cells called monocytes and immature myeloid cells, which can accumulate in the bone marrow, liver, spleen, and lymph nodes.

CBL gene mutations are found in approximately 10-15% of JMML cases. The CBL gene provides instructions for making a protein that helps regulate cell growth and division. When the CBL gene is mutated, it can lead to the uncontrolled growth and division of cells, which can contribute to the development of cancer.

Symptoms of CBL Gene JMML

• Anemia (low red blood cell count)
• Thrombocytopenia (low platelet count)
• Recurrent infections
• Enlarged liver and spleen
• Fever
• Abdominal pain
• Skin rash
• Bleeding
• Bruising
• Weight loss

Diagnosis of CBL Gene JMML

Diagnosis of CBL gene JMML involves a combination of clinical examination, blood tests, and bone marrow analysis. The following tests may be performed:

• Complete blood count (CBC)
• Bone marrow biopsy and aspiration
• Genetic testing for CBL gene mutations

NGS Genetic DNA Test for CBL Gene JMML at DNA Labs India

DNA Labs India offers a Next Generation Sequencing (NGS) Genetic DNA Test for CBL Gene JMML. This test can detect germline mutations in the CBL gene that may increase the risk of developing JMML. The test is performed using a small blood sample and provides accurate and reliable results.

Cost of NGS Genetic DNA Test for CBL Gene JMML

The cost of NGS Genetic DNA Test for CBL Gene JMML at DNA Labs India is INR 20,000.

Conclusion

CBL Gene Juvenile Myelomonocytic Leukemia is a rare but serious condition that can affect children. If you or your child is experiencing symptoms of JMML, it is important to seek medical attention promptly. DNA Labs India offers accurate and reliable NGS Genetic DNA Test for CBL Gene JMML at an affordable cost. Contact us today to schedule an appointment.