Short Description

NGS genetic DNA test detecets for variant and mutation detection in CASP10 gene for Autoimmune lymphoproliferative syndrome type 2A

PreTest Information

Clinical History of Patient who is going for CASP10 Gene Autoimmune lymphoproliferative syndrome type 2A NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CASP10 Gene Autoimmune lymphoproliferative syndrome type 2A NGS Genetic DNA Test gene CASP10

Detail Description

CASP10 Gene Autoimmune Lymphoproliferative Syndrome Type 2A NGS Genetic DNA Test

Autoimmune lymphoproliferative syndrome (ALPS) is a rare genetic disorder that affects the immune system. It is caused by mutations in the genes that regulate cell death, leading to the accumulation of lymphocytes in the body and an increased risk of autoimmune diseases and lymphoma. ALPS can be caused by mutations in different genes, including CASP10, which is associated with ALPS type 2A.

Symptoms of ALPS Type 2A

The symptoms of ALPS type 2A can vary from person to person, but they typically include:

• Enlarged lymph nodes, liver, and spleen
• Autoimmune disorders, such as autoimmune hemolytic anemia, thrombocytopenia, and neutropenia
• Increased susceptibility to infections
• Lymphoma

Diagnosis of ALPS Type 2A

ALPS type 2A can be diagnosed through genetic testing, which involves sequencing the CASP10 gene. This test can identify mutations in the gene that are associated with ALPS type 2A. Other tests, such as blood tests and imaging studies, may also be used to confirm the diagnosis and assess the extent of the disease.

NGS Genetic DNA Test for ALPS Type 2A

DNA Labs India offers a Next-Generation Sequencing (NGS) genetic DNA test for ALPS type 2A that can identify mutations in the CASP10 gene. This test is highly accurate and can provide a definitive diagnosis of ALPS type 2A. The cost of the test is INR 20,000.

Benefits of NGS Genetic DNA Test

The NGS genetic DNA test for ALPS type 2A has several benefits, including:

• High accuracy: The test is highly accurate and can detect even small mutations in the CASP10 gene.
• Early diagnosis: Early diagnosis of ALPS type 2A can help to prevent complications and improve outcomes.
• Personalized treatment: Knowing the genetic cause of ALPS type 2A can help to personalize treatment and improve outcomes.

Conclusion

The NGS genetic DNA test for ALPS type 2A offered by DNA Labs India is a highly accurate and reliable test that can provide a definitive diagnosis of this rare genetic disorder. Early diagnosis and personalized treatment can help to prevent complications and improve outcomes for individuals with ALPS type 2A.