Short Description

NGS genetic DNA test detecets for variant and mutation detection in CARD14 gene for Pityriasis rubra pilaris

PreTest Information

Clinical History of Patient who is going for CARD14 Gene Pityriasis rubra pilaris NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CARD14 Gene Pityriasis rubra pilaris NGS Genetic DNA Test gene CARD14

Detail Description

DNA Labs India - CARD14 Gene Pityriasis rubra pilaris NGS Genetic DNA Test

Pityriasis rubra pilaris (PRP) is a rare inflammatory skin disorder that affects both children and adults. It is characterized by the development of reddish-orange scaly patches with well-defined borders and tiny bumps that resemble chicken skin. The cause of PRP is not yet fully understood, but recent studies have linked it to mutations in the CARD14 gene.

The CARD14 Gene

The CARD14 gene provides instructions for making a protein that is involved in the immune system's response to infection and inflammation. Mutations in this gene have been found to cause a variety of skin disorders, including PRP. These mutations result in the production of a faulty protein that triggers the immune system to attack healthy skin cells, leading to the development of PRP.

NGS Genetic DNA Test

DNA Labs India offers a Next-Generation Sequencing (NGS) Genetic DNA Test for the CARD14 gene mutation associated with PRP. This test can identify mutations in the CARD14 gene that may be responsible for the development of PRP. The test is performed using a small sample of blood or saliva and can be completed in just a few days.

Symptoms of PRP

The symptoms of PRP can vary from person to person, but typically include:

• Reddish-orange scaly patches on the skin
• Tiny bumps on the skin that resemble chicken skin
• Dry, flaky skin
• Itching
• Joint pain and stiffness
• Fever
• Fatigue

Diagnosis of PRP

Diagnosis of PRP is usually made by a dermatologist based on the appearance of the skin lesions and the patient's medical history. A skin biopsy may also be performed to confirm the diagnosis. The NGS Genetic DNA Test offered by DNA Labs India can provide additional information to aid in the diagnosis of PRP.

Cost of NGS Genetic DNA Test

The cost of the NGS Genetic DNA Test for the CARD14 gene mutation associated with PRP is INR 20,000.

Contact DNA Labs India today to learn more about our NGS Genetic DNA Test for the CARD14 gene mutation associated with PRP.