Short Description

NGS genetic DNA test detecets for variant and mutation detection in CACNA1A gene for Familial hemiplegic migraine type 1

PreTest Information

Clinical History of Patient who is going for CACNA1A Gene Familial hemiplegic migraine type 1 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with CACNA1A Gene Familial hemiplegic migraine type 1

Detail Description

CACNA1A Gene Familial Hemiplegic Migraine Type 1 NGS Genetic DNA Test Cost INR: 20000 Symptoms Diagnosis

Familial hemiplegic migraine (FHM) is a rare genetic disorder that causes severe migraine headaches, often accompanied by temporary paralysis on one side of the body. FHM is caused by mutations in several different genes, including the CACNA1A gene. The CACNA1A gene provides instructions for making a protein that helps regulate the flow of calcium ions into cells, which is important for proper brain function.

Symptoms of FHM

The symptoms of FHM can vary from person to person, but typically include:

• Severe headache on one side of the head
• Nausea and vomiting
• Sensitivity to light and sound
• Temporary paralysis on one side of the body
• Visual disturbances, such as seeing flashing lights or zigzag lines

These symptoms can last for several hours or even days, and can be debilitating for those who experience them.

Diagnosis of FHM

Diagnosing FHM can be challenging, as it is a rare disorder and its symptoms can be similar to those of other types of migraines. A doctor may perform a physical exam and take a detailed medical history to rule out other conditions. Genetic testing can also be used to confirm a diagnosis of FHM.

CACNA1A Gene Testing

Testing for mutations in the CACNA1A gene can help confirm a diagnosis of FHM. This type of testing is called next-generation sequencing (NGS) genetic DNA testing. NGS is a powerful tool that can sequence large amounts of DNA quickly and accurately. It can detect mutations in the CACNA1A gene with high sensitivity and specificity, making it a reliable method for diagnosing FHM.

Cost of CACNA1A Gene Testing

The cost of CACNA1A gene testing can vary depending on the laboratory and the specific test being used. At DNA Labs India, we offer NGS genetic DNA testing for the CACNA1A gene at a cost of INR 20,000. This test includes sequencing of the entire coding region of the gene, as well as the surrounding non-coding regions, to ensure the most comprehensive analysis possible.

Conclusion

Familial hemiplegic migraine type 1 is a rare genetic disorder that can cause severe migraine headaches, temporary paralysis, and other symptoms. Diagnosis can be challenging, but genetic testing for mutations in the CACNA1A gene can help confirm a diagnosis of FHM. At DNA Labs India, we offer NGS genetic DNA testing for the CACNA1A gene at a cost of INR 20,000, providing a reliable and comprehensive analysis for those with suspected FHM.

For more information about CACNA1A gene testing or to schedule a test, please contact DNA Labs India today.