Short Description

NGS genetic DNA test detecets for variant and mutation detection in C9orf72 gene for Amyotrophic lateral sclerosis with frontotemporal dementia

PreTest Information

Clinical History of Patient who is going for C9orf72 Gene Amyotrophic lateral sclerosis with frontotemporal dementia NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with C9orf72 Gene Amyotrophic lateral sclerosis with frontotemporal dementia

Detail Description

C9orf72 Gene Amyotrophic lateral sclerosis with frontotemporal dementia NGS Genetic DNA Test

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Frontotemporal dementia (FTD) is a type of dementia that affects the frontal and temporal lobes of the brain. ALS with FTD is a rare form of neurodegenerative disease that affects both the motor neurons and the frontal and temporal lobes of the brain.

The C9orf72 gene has been identified as a major genetic cause of ALS with FTD. The C9orf72 gene is located on chromosome 9 and codes for a protein of unknown function. Mutations in this gene have been associated with a wide range of neurological disorders, including ALS with FTD.

Symptoms of ALS with FTD

The symptoms of ALS with FTD can vary depending on the individual. In general, the disease begins with muscle weakness and wasting, which can affect the arms, legs, and torso. As the disease progresses, individuals may experience difficulty speaking, swallowing, and breathing. In addition to these motor symptoms, individuals with ALS with FTD may also experience changes in their behavior and personality. This can include apathy, social withdrawal, and disinhibition.

Diagnosis of ALS with FTD

Diagnosing ALS with FTD can be challenging, as there is no single test that can definitively diagnose the disease. Diagnosis typically involves a combination of physical examination, medical history, and imaging tests. Genetic testing can also be used to identify mutations in the C9orf72 gene.

NGS Genetic DNA Test

The NGS Genetic DNA Test is a powerful tool for identifying mutations in the C9orf72 gene. This test uses next-generation sequencing (NGS) technology to analyze the DNA sequence of the gene and identify any mutations that may be present. The test is highly accurate and can detect even small mutations that may be missed by other genetic testing methods.

Cost of NGS Genetic DNA Test

The cost of the NGS Genetic DNA Test for ALS with FTD is INR 20,000. This includes the cost of the test itself, as well as any necessary counseling and support services.

Conclusion

The C9orf72 gene is a major genetic cause of ALS with FTD. The NGS Genetic DNA Test is a powerful tool for identifying mutations in this gene, which can help with diagnosis and treatment. If you or a loved one are experiencing symptoms of ALS with FTD, it is important to seek medical attention and consider genetic testing.

At DNA Labs India, we offer a range of genetic testing services, including the NGS Genetic DNA Test for ALS with FTD. Our team of experts is dedicated to providing accurate and reliable genetic testing services, as well as counseling and support for individuals and families affected by neurological disorders.

Contact us today to learn more about our services and how we can help you.