Short Description

C1 esterase is decreased in Angioedema. The inherited form is usually diagnosed in the first two decades of life. The acquired form affects primarily adults with autoimmune or lymphoproliferative disorders. Approximately 15% of patients with Hereditary angioedema have a normal concentration of the protein but it is dysfunctional.

PreTest Information

No special preparation required. Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Detail Description

C1 Esterase Inhibitor Functional & C1 Inactivator Functional Test

If you are experiencing swelling in different areas of your body, you might be suffering from a rare genetic disorder called Hereditary Angioedema (HAE). This condition occurs due to the deficiency or dysfunction of the C1 esterase inhibitor (C1-INH) protein, which regulates the production of bradykinin, a peptide that causes swelling. To diagnose HAE, DNA Labs India offers C1 Esterase Inhibitor Functional and C1 Inactivator Functional Test.

Symptoms of Hereditary Angioedema (HAE)

The symptoms of HAE vary from person to person and can include:

• Swelling of the face, lips, tongue, throat, and extremities
• Abdominal pain, nausea, and vomiting
• Difficulty breathing
• Joint pain
• Diarrhea
• Headache
• Fatigue

The symptoms can last from hours to days and are often unpredictable. They can be triggered by stress, hormonal changes, infections, trauma, and other factors.

Diagnosis of Hereditary Angioedema (HAE)

The diagnosis of HAE requires a thorough medical history, physical examination, and laboratory tests. The C1 Esterase Inhibitor Functional and C1 Inactivator Functional Test are the most reliable tests for HAE, as they measure the activity and quantity of C1-INH and C1-esterase, which are essential components of the complement system.

These tests can be done with a blood sample and are usually performed when a person is not experiencing an acute attack. The results can help confirm or rule out HAE and guide the treatment plan.

Test Cost of C1 Esterase Inhibitor Functional and C1 Inactivator Functional Test

The cost of the C1 Esterase Inhibitor Functional and C1 Inactivator Functional Test at DNA Labs India is INR 9000. This is an affordable price for a test that can provide accurate and timely diagnosis of HAE, which can be a life-threatening condition if left untreated.

If you have any of the symptoms of HAE or a family history of the condition, don't hesitate to get tested. Early diagnosis and treatment can help prevent severe attacks and improve your quality of life.

Contact DNA Labs India today to schedule your C1 Esterase Inhibitor Functional and C1 Inactivator Functional Test.