Short Description

Beta Thalassemia-HBB Full Gene Analysis (Couple) is performed using Sanger Sequencing methodology. Sample that have to be given is Peripheral blood in EDTA Vacutainer (2ml) for this test. You can expect results in 8-10 days

PreTest Information

Beta Thalassemia-HBB Full Gene Analysis (Couple) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

Beta Thalassemia-HBB Full Gene Analysis (Couple) cost INR:15000 symptoms diagnosis

Beta thalassemia is a genetic blood disorder that affects the production of hemoglobin, a protein responsible for carrying oxygen throughout the body. It is caused by mutations in the HBB gene, which provides instructions for making beta-globin, a subunit of hemoglobin.

People who inherit two copies of mutated HBB genes from their parents develop beta thalassemia major, a severe form of the disease that requires lifelong blood transfusions and other treatments. People who inherit one mutated HBB gene and one normal HBB gene from their parents develop beta thalassemia trait, a milder form of the disease that usually does not cause symptoms.

Beta thalassemia is most commonly found in people of Mediterranean, Middle Eastern, and South Asian descent. It can be diagnosed through a blood test that measures the amount of hemoglobin and the types of hemoglobin in the blood. A genetic test that analyzes the HBB gene can confirm the diagnosis and determine the specific mutations causing the disease.

Symptoms of beta thalassemia

The symptoms of beta thalassemia vary depending on the severity of the disease. People with beta thalassemia major usually develop symptoms within the first two years of life, while people with beta thalassemia trait may not have any symptoms or may have mild symptoms.

Common symptoms of beta thalassemia major include:

• Severe anemia
• Jaundice
• Enlarged spleen
• Delayed growth and development
• Facial bone deformities
• Heart problems
• Frequent infections

Common symptoms of beta thalassemia trait include:

• Mild anemia
• Fatigue
• Weakness
• Shortness of breath

Diagnosis of beta thalassemia

Beta thalassemia can be diagnosed through a blood test that measures the amount of hemoglobin and the types of hemoglobin in the blood. A genetic test that analyzes the HBB gene can confirm the diagnosis and determine the specific mutations causing the disease.

At DNA Labs India, we offer beta thalassemia-HBB full gene analysis for couples who are planning to have children. This test analyzes the entire HBB gene to determine if either partner carries any mutations that could cause beta thalassemia in their children.

Cost of beta thalassemia-HBB full gene analysis (couple)

The cost of beta thalassemia-HBB full gene analysis for couples at DNA Labs India is INR 15000. This includes genetic counseling with a certified genetic counselor to discuss the results of the test and any implications for future pregnancies.

Conclusion

Beta thalassemia is a genetic blood disorder that affects the production of hemoglobin. It can be diagnosed through a blood test that measures the amount of hemoglobin and the types of hemoglobin in the blood. A genetic test that analyzes the HBB gene can confirm the diagnosis and determine the specific mutations causing the disease. At DNA Labs India, we offer beta thalassemia-HBB full gene analysis for couples who are planning to have children, at a cost of INR 15000. This test can help identify if either partner carries any mutations that could cause beta thalassemia in their children, and can provide peace of mind for couples who want to start a family.