BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test Cost 5000 Rs

BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test

BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test

Disease: Leukemia

Method: Real Time PCR

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Sample Types
  • 5 mL (3 mL min.) whole blood / Bone marrow in 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.

5,000.00/- Rs ₹6,000.0016% off

  • Results in : Sample Mon / Wed / Fri by 9 am; Report Tue / Thu / Sat
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BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test Cost 5000 Rs

Test Name BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test
Test type Oncologist, Hematologist
Pre-test Information No special preparation required
Report Delivery Sample Mon / Wed / Fri by 9 am; Report Tue / Thu / Sat
Components
Price ₹ 5000
Method Real Time PCR

BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test Details

Short Description

BCR-ABL is a fusion gene formed by the re-arrangement of breakpoint cluster region (BCR) on chromosome 22 with the ABL protooncogene on chromosome 9 leading to the formation of Philadelphia chromosome. This re-arrangement is seen in almost 95% patients with CML.

Test Specifications

  • Speciality: Oncologist, Hematologist

  • Components:

  • Department: MOLECULAR DIAGNOSTICS

  • Shipping Stability: Room Temperature: NA, Refrigerator:4 days, Frozen: NA

PreTest Information

No special preparation required

Detail Description

BCR-ABL Gene Rearrangement PCR Qualitative Test: Cost, Symptoms, and Diagnosis

BCR-ABL gene rearrangement is a genetic abnormality that occurs in some blood cells. This abnormality is associated with chronic myeloid leukemia (CML) and some types of acute lymphoblastic leukemia (ALL). To test for the presence of BCR-ABL gene rearrangement, a PCR qualitative test is required. DNA Labs India offers this test at a cost of INR 5000.

What is BCR-ABL Gene Rearrangement?

BCR-ABL gene rearrangement is a genetic abnormality that occurs when the BCR (breakpoint cluster region) gene on chromosome 22 and the ABL (Abelson) gene on chromosome 9 swap genetic material. This fusion creates a new gene, called the BCR-ABL gene. The BCR-ABL gene produces a protein that promotes the uncontrolled growth of white blood cells, leading to leukemia.

What are the Symptoms of BCR-ABL Gene Rearrangement?

The symptoms of BCR-ABL gene rearrangement depend on the type of leukemia it causes. In CML, symptoms may include:

  • Fatigue
  • Weight loss
  • Abdominal pain or discomfort
  • Sweating, especially at night
  • Fever
  • Enlarged spleen

In ALL, symptoms may include:

  • Fever
  • Weakness
  • Pale skin
  • Bleeding and bruising easily
  • Pain in the bones or joints
  • Swollen lymph nodes

How is BCR-ABL Gene Rearrangement Diagnosed?

BCR-ABL gene rearrangement is diagnosed using a PCR qualitative test. This test detects the presence of the BCR-ABL gene in a sample of blood or bone marrow. PCR (polymerase chain reaction) is a technique that amplifies a specific region of DNA, making it easier to detect. A qualitative PCR test determines whether the BCR-ABL gene is present or absent in the sample. If the gene is present, it is an indication of BCR-ABL gene rearrangement and possible leukemia.

Conclusion

PCR qualitative test for BCR-ABL gene rearrangement is crucial for the diagnosis of leukemia. It helps in identifying the type of leukemia and the required treatment. DNA Labs India offers this test at an affordable cost of INR 5000. If you are experiencing symptoms of leukemia or have a family history of the disease, it is essential to get tested for BCR-ABL gene rearrangement.

Contact DNA Labs India to book your PCR qualitative test for BCR-ABL gene rearrangement today!

Frequently Asked Questions

  • What is the cost of BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test?

    Cost of BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test is 5000 Rs

  • What is BCR ABL?

    People normally have 46 chromosomes, divided into 23 pairs, in each cell. One of each pair of chromosomes comes from your mother, and the other pair comes from your father. BCR-ABL is a mutation that is formed by the combination of two genes, known as BCR and ABL. It's sometimes called a fusion gene.

     

  • What happens during a BCR-ABL genetic test?

    If you are getting a blood test, a health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

  • Why do I need a BCR-ABL genetic test?

    You may need a BCR-ABL test if you have symptoms of chronic myeloid leukaemia (CML) or Ph-positive acute lymphoblastic leukaemia (ALL). These include:

    • Fever
    • Weight loss
    • Night sweats (excessive sweating while sleeping)
    • Joint or bone pain

  • Are there any risks to the test?

    There is very little risk to having a blood test. You may have slight pain or bruise at the spot where the needle was put in, but most symptoms go away quickly. After a bone marrow test, you may feel stiff or sore at the injection site. This usually goes away in a few days. Your health care provider may recommend or prescribe a pain reliever to help.

  • What do the results mean?

    If your results show you have the BCR-ABL gene, as well as an abnormal amount of white blood cells, you will probably be diagnosed with chronic myeloid leukaemia (CML) or Ph-positive, acute lymphoblastic leukaemia (ALL).

  • How is the test used?

    BCR-ABL1 testing is used to help diagnose some forms of leukaemia, i.e., chronic myelogenous leukaemia (CML) or a type of acute lymphoblastic leukaemia (ALL) and, rarely, acute myeloid leukaemia (AML) in which the BCR-ABL1 gene sequence is present (BCR-ABL1-positive).

  • What is the cost of the BCR-ABL test?

    The cost of the BCR-ABL Test is 5000 Rs

  • How many days does it take for reports?

    Reports will take 8-10 working days

₹5,000.00 ₹6,000.0016% off

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