List of genes tested using NGS technology for detection of variant and mutation in Ataxia comprehensive panel are ABCB7, ABHD12, ABHD5, ACADVL, ACO2, AFG3L2, AHI1, ALDH5A1, AMACR, ANO10, AP1S2, APTX, ARL13B, ARL6, ARSA, ATCAY, ATM, ATN1, ATP13A2, ATP1A3, ATP2B3, ATP8A2, ATXN1, ATXN10, ATXN2, ATXN3, ATXN7, ATXN8OS, B9D1, BBS1, BBS12, BEAN1, BSCL2, BTD, C12ORF65, C19orf12, CA8, CACNA1A, CACNB4, CAMTA1, CASK, CC2D2A, CCDC88C, CEP290, CEP41, CHMP1A, CLCN2, CLN5, CLN6, CLPP, COASY, COQ2, COQ8A, COQ9, COX20, CP, CPLANE1, CSPP1, CWF19L1, CYP27A1, DARS2, DLAT, DNAJC19, DNAJC5, DNMT1, EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5, ELOVL4, ELOVL5, EXOSC3, FA2H, FBXL4, FGF14, FLVCR1, FTL, FXN, GALC, GBA, GBA2, GFAP, GJB1, GJC2, GOSR2, GRID2, GRM1, GSS, HEPACAM, HEXB, HIBCH, INPP5E, ITM2B, ITPR1, KCNA1, KCNC3, KCND3, KCNJ10, KIF1A, KIF1C, KIF5A, KIF7, LAMA1, LMNB1, LRPPRC, MARS2, MKS1, MLC1, MRE11, MTFMT, MTPAP, MTTP, NDUFAF6, NDUFS1, NDUFS2, NDUFS4, NDUFS7, NDUFV1, NOP56, NPC1, NPC2, NPHP1, NUBPL, OFD1, OPA1, OPA3, OPHN1, PANK2, PAX6, PDHX, PDSS1, PDSS2, PDYN, PEX10, PEX2, PEX7, PHYH, PLA2G6, PLP1, PNKD, PNKP, PNPLA6, POLG, POLR3A, POLR3B, PPP2R2B, PRICKLE1, PRKCG, PRRT2, RARS2, RPGRIP1L, RRM2B, RUBCN, SACS, SCN2A, SETX, SIL1, SLC16A2, SLC17A5, SLC1A3, SLC20A2, SLC25A46, SLC2A1, SLC52A3, SLC9A6, SPG11, SPG7, SPR, SPTBN2, STUB1, SYNE1, TBP, TCTN2, TGM6, TMEM216, TMEM237, TMEM240, TMEM67, TPP1, TSEN2, TSEN34, TSEN54, TTBK2, TTC19, TTPA, TUBB4A, TWNK, UBA5, VAMP1, VLDLR, VRK1, WDR81, WFS1, WWOX, ZFYVE26
Ataxia Comprehensive Panel NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis
Ataxia is a neurological disorder that affects coordination and balance. It can be caused by a variety of genetic and non-genetic factors, making it difficult to diagnose and treat. DNA Labs India offers an Ataxia Comprehensive Panel NGS Genetic DNA Test that can help diagnose the underlying cause of ataxia and guide treatment.
Symptoms of Ataxia
The symptoms of ataxia can vary depending on the underlying cause and severity of the condition. Common symptoms include:
- Loss of coordination and balance
- Difficulty walking or standing
- Trouble with fine motor skills, such as writing or buttoning a shirt
- Slurred speech
- Difficulty swallowing
- Eye movement abnormalities
- Tremors or jerky movements
- Weakness or numbness in the limbs
These symptoms can be mild or severe, and may worsen over time. If you are experiencing any of these symptoms, it is important to see a doctor for a proper diagnosis.
Diagnosing Ataxia
Diagnosing ataxia can be challenging, as there are many potential causes and symptoms can be similar to other neurological disorders. A thorough medical history and physical exam can help identify potential underlying causes, but additional testing is often needed.
The Ataxia Comprehensive Panel NGS Genetic DNA Test offered by DNA Labs India can help diagnose ataxia by identifying genetic mutations that may be contributing to the condition. This test uses next-generation sequencing (NGS) technology to analyze multiple genes associated with ataxia, providing a comprehensive analysis that can guide treatment.
The Cost of the Ataxia Comprehensive Panel NGS Genetic DNA Test
The cost of the Ataxia Comprehensive Panel NGS Genetic DNA Test from DNA Labs India is INR 20000. This includes the cost of the test itself, as well as any necessary counseling and support services. While this may seem like a significant investment, it is important to remember that a proper diagnosis is essential for effective treatment.
Why Choose DNA Labs India?
DNA Labs India is a leading provider of genetic testing services in India, offering a wide range of tests for both clinical and research purposes. Our team of experienced genetic counselors and scientists are dedicated to providing accurate and reliable results, as well as personalized support and guidance throughout the testing process.
If you or a loved one is experiencing symptoms of ataxia, the Ataxia Comprehensive Panel NGS Genetic DNA Test from DNA Labs India may be able to help. Contact us today to learn more about our services and schedule your test.
Conclusion
Ataxia is a complex neurological disorder that can be challenging to diagnose and treat. The Ataxia Comprehensive Panel NGS Genetic DNA Test offered by DNA Labs India can help identify the underlying cause of ataxia and guide treatment for improved outcomes. With a cost of INR 20000, this test is a valuable investment for anyone experiencing symptoms of ataxia. Contact DNA Labs India today to learn more about our services and schedule your test.
The Ataxia Comprehensive Panel is a genetic test that uses Next-Generation Sequencing (NGS) technology to analyze a set of genes associated with various types of ataxia, which is a group of neurological disorders characterized by impaired coordination and balance. This panel aims to identify genetic mutations or variants that might be contributing to the development of ataxia in an individual.
The panel typically includes a comprehensive set of genes that have been linked to different forms of ataxia, including both autosomal dominant and recessive forms. Some of the genes commonly included in an Ataxia Comprehensive Panel may include, but are not limited to:
- ATXN1: Associated with Spinocerebellar Ataxia Type 1 (SCA1).
- ATXN2: Associated with Spinocerebellar Ataxia Type 2 (SCA2).
- ATXN3: Associated with Spinocerebellar Ataxia Type 3 (SCA3), also known as Machado-Joseph Disease.
- ATXN7: Associated with Spinocerebellar Ataxia Type 7 (SCA7).
- ATXN8OS: Associated with Spinocerebellar Ataxia Type 8 (SCA8).
- ATXN10: Associated with Spinocerebellar Ataxia Type 10 (SCA10).
- ATXN17: Associated with Spinocerebellar Ataxia Type 17 (SCA17).
- ATXN29: Associated with Spinocerebellar Ataxia Type 29.
- CACNA1A: Associated with Spinocerebellar Ataxia Type 6 (SCA6) and episodic ataxia type 2.
- TBP: Associated with Spinocerebellar Ataxia Type 17 (SCA17).
- PRKCG: Associated with Spinocerebellar Ataxia Type 14 (SCA14).
- GRID2: Associated with Spinocerebellar Ataxia Type 27.
- SPG7: Associated with Spinocerebellar Ataxia Type 7 (SCA7).
The specific genes included in the panel may vary depending on the laboratory and the version of the panel being used. The test involves extracting DNA from the patient's sample (usually blood or saliva), sequencing the relevant genes, and analyzing the sequencing data to identify any pathogenic or potentially pathogenic mutations.
It's important to note that genetic testing, including the Ataxia Comprehensive Panel, is typically recommended and interpreted by medical professionals, genetic counselors, or specialists who can provide appropriate guidance and counseling based on the results. The results of the test can provide valuable insights into the genetic basis of ataxia, which can aid in diagnosis, prognosis, and personalized treatment recommendations.
