Short Description

NGS genetic DNA test detecets for variant and mutation detection in APOL1 gene for Focal segmental glomerulosclerosis type 4, susceptibility to

PreTest Information

Clinical History of Patient who is going for APOL1 Gene Focal segmental glomerulosclerosis type 4, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with APOL1 Gene Focal segmental glomerulosclerosis type 4, susceptibility to NGS Genetic DNA Test gene APOL1

Detail Description

APOL1 Gene Focal Segmental Glomerulosclerosis Type 4: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

APOL1 gene Focal Segmental Glomerulosclerosis Type 4 is a genetic condition that affects the kidneys. It is caused by mutations in the APOL1 gene, which provides instructions for making a protein that is involved in the regulation of cell death and inflammation.

People with APOL1 gene mutations have an increased risk of developing Focal Segmental Glomerulosclerosis (FSGS), a condition that affects the filtering units of the kidneys called glomeruli. FSGS can lead to kidney damage and ultimately kidney failure.

Symptoms of APOL1 Gene Focal Segmental Glomerulosclerosis Type 4

The symptoms of APOL1 gene Focal Segmental Glomerulosclerosis Type 4 can vary from person to person, and some people may not experience any symptoms at all. However, common symptoms may include:

• Proteinuria (excess protein in the urine)
• Hematuria (blood in the urine)
• Edema (swelling in the legs, ankles, and feet)
• High blood pressure
• Fatigue
• Decreased urine output
• Weight gain

Diagnosis of APOL1 Gene Focal Segmental Glomerulosclerosis Type 4

Diagnosing APOL1 gene Focal Segmental Glomerulosclerosis Type 4 typically involves a combination of medical history, physical examination, laboratory tests, and imaging studies. Your doctor may order a urine test to check for protein and blood, a blood test to check for kidney function and genetic testing to detect APOL1 gene mutations.

If your doctor suspects you have FSGS, they may also order a kidney biopsy, in which a small sample of kidney tissue is removed and examined under a microscope. This can help confirm the diagnosis and determine the extent of kidney damage.

NGS Genetic DNA Test Cost

NGS Genetic DNA Test cost for APOL1 gene Focal Segmental Glomerulosclerosis Type 4 in India is around INR 20,000. This test is performed using Next-Generation Sequencing technology to analyze the DNA sequence of the APOL1 gene and detect any mutations that may be present.

NGS Genetic DNA Test is a non-invasive and painless procedure that involves collecting a sample of your saliva or blood. The sample is then sent to a laboratory for analysis, and the results are typically available within a few weeks.

Conclusion

APOL1 gene Focal Segmental Glomerulosclerosis Type 4 is a genetic condition that can lead to kidney damage and failure. If you are experiencing any of the symptoms mentioned above, it is important to consult a doctor for proper diagnosis and treatment. NGS Genetic DNA Test cost for APOL1 gene Focal Segmental Glomerulosclerosis Type 4 is INR 20,000, and it can help detect any mutations in the APOL1 gene and determine your risk of developing FSGS.

Early detection and treatment of APOL1 gene Focal Segmental Glomerulosclerosis Type 4 can help slow the progression of kidney damage and improve your quality of life.

For more information on APOL1 gene Focal Segmental Glomerulosclerosis Type 4 and NGS Genetic DNA Test, you can contact DNA Labs India.