Short Description

AML FISH PANEL (FISH [AML/ETO, inv(16), PML/RARA, MLL]) is performed using FISH methodology. Sample that have to be given is Bone marrow / Peripheral blood (Transport immediately) in Sodium Heparin Vacutainer (2ml) for this test. You can expect results in 5-7 days

PreTest Information

AML FISH PANEL (FISH [AML/ETO, inv(16), PML/RARA, MLL]) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

AML FISH PANEL: Cost, Symptoms, and Diagnosis

Acute myeloid leukemia (AML) is a type of cancer that affects the blood and bone marrow. It is caused by abnormal growth and division of immature cells that should develop into white blood cells, red blood cells, or platelets. In AML, these cells do not mature properly and accumulate in the bone marrow, leading to low blood cell counts and other complications.

AML is diagnosed through various tests, including blood tests, bone marrow biopsy, and genetic testing. One of the genetic tests commonly used to diagnose AML is the AML FISH panel.

What is the AML FISH panel?

The AML FISH panel is a genetic test that looks for specific changes in the DNA of AML cells. FISH stands for fluorescent in situ hybridization, which is a technique used to visualize and count specific genes or chromosomes in individual cells.

The AML FISH panel tests for four genetic abnormalities that are commonly found in AML:

• AML/ETO (t(8;21))
• inv(16)
• PML/RARA (t(15;17))
• MLL (11q23)

These abnormalities are associated with different subtypes of AML and can help determine the prognosis and treatment options for patients.

What are the symptoms of AML?

The symptoms of AML can vary depending on the stage and severity of the disease. Some common symptoms include:

• Fatigue and weakness
• Shortness of breath
• Fever and chills
• Easy bruising and bleeding
• Swollen lymph nodes
• Unexplained weight loss
• Bone pain
• Headaches

If you are experiencing any of these symptoms, it is important to see a doctor for a proper diagnosis and treatment.

How is AML diagnosed?

AML is typically diagnosed through a combination of tests, including:

• Complete blood count (CBC) to check for low blood cell counts
• Bone marrow biopsy to examine the bone marrow cells for abnormalities
• Genetic testing, including the AML FISH panel, to look for specific genetic abnormalities

The results of these tests can help determine the subtype of AML and the best treatment options for the patient.

What is the cost of the AML FISH panel in India?

The cost of the AML FISH panel in India can vary depending on the laboratory and location. At DNA Labs India, the cost of the AML FISH panel is INR 14,850.

This cost includes the test kit, sample collection, transportation, analysis, and interpretation of results by a team of experienced geneticists and pathologists. Results are typically available within 5-7 working days after the sample is received by the laboratory.

Conclusion

The AML FISH panel is a valuable tool for diagnosing AML and determining the best treatment options for patients. If you are experiencing symptoms of AML or have been diagnosed with AML, it is important to discuss the AML FISH panel with your doctor to determine if it is a necessary test for your diagnosis and treatment.