Short Description

This assay is usd for the detection of AML-ETO [AML1(CBFA2, RUNX1)-ETO (MTG8)] fusion gene transcript formed due to translocation between chromosome 8 and 21 which is associated with Acute myeloid leukemia.

PreTest Information

No special preparation required

Detail Description

AML ETO t(821) GENE REARRANGEMENT PCR QUALITATIVE Test Cost and Symptoms Diagnosis

Acute Myeloid Leukemia (AML) is a type of cancer that affects the blood and bone marrow. It is a rapidly progressing disease that requires early diagnosis and treatment. One of the tests used to diagnose AML is the AML ETO t(821) Gene Rearrangement PCR Qualitative Test. This test helps in identifying a specific genetic rearrangement that is associated with AML. DNA Labs India offers this test at a cost of INR 6000.

What is AML ETO t(821) Gene Rearrangement?

The AML ETO t(821) Gene Rearrangement is a specific genetic alteration that is found in a subset of patients with AML. It is caused by a translocation of genetic material between chromosomes 8 and 21, resulting in the fusion of two genes: the AML1 gene on chromosome 21 and the ETO gene on chromosome 8. This fusion gene produces a protein that is not normally present in healthy cells and is associated with the development of AML.

What is the AML ETO t(821) Gene Rearrangement PCR Qualitative Test?

The AML ETO t(821) Gene Rearrangement PCR Qualitative Test is a molecular diagnostic test that uses Polymerase Chain Reaction (PCR) technology to detect the presence of the AML ETO t(821) gene rearrangement. The test is performed on a blood or bone marrow sample and can identify the specific genetic alteration associated with AML. This test is highly sensitive and specific and can detect even low levels of the fusion gene.

What are the Symptoms of AML?

AML is a rapidly progressing disease that can cause a variety of symptoms. Some of the common symptoms of AML include:

• Fever and chills
• Fatigue
• Shortness of breath
• Easy bruising or bleeding
• Joint pain or swelling
• Enlarged lymph nodes
• Unexplained weight loss
• Pale skin
• Loss of appetite

How is AML Diagnosed?

AML is diagnosed through a combination of tests and procedures. These may include:

• Physical exam and medical history
• Blood tests
• Bone marrow biopsy
• Cytogenetic analysis
• Molecular testing, such as the AML ETO t(821) Gene Rearrangement PCR Qualitative Test

The Cost of AML ETO t(821) Gene Rearrangement PCR Qualitative Test

The AML ETO t(821) Gene Rearrangement PCR Qualitative Test is offered by DNA Labs India at a cost of INR 6000. This cost includes the test kit, sample collection, and analysis of the test results. DNA Labs India is a trusted provider of molecular diagnostic testing in India and offers a wide range of tests to aid in the diagnosis and treatment of various diseases.

Conclusion

The AML ETO t(821) Gene Rearrangement PCR Qualitative Test is a valuable tool in the diagnosis of AML. This test can identify a specific genetic alteration associated with AML and aid in the development of targeted treatment plans. DNA Labs India offers this test at a cost of INR 6000 and is committed to providing accurate and reliable diagnostic testing services for patients across India.