Short Description

NGS genetic DNA test detecets for variant and mutation detection in AIP gene for Pituitary adenoma, prolactin-secreting, due to AIP germline mutation

PreTest Information

Clinical History of Patient who is going for AIP Gene Pituitary adenoma, prolactin-secreting, due to AIP germline mutation NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with AIP Gene Pituitary adenoma, prolactin-secreting, due to AIP germline mutation NGS Genetic DNA Test gene AIP

Detail Description

AIP Gene Pituitary Adenoma: Symptoms, Diagnosis and NGS Genetic DNA Test Cost

Pituitary adenomas are benign tumors that arise from the pituitary gland. These tumors can cause hormonal imbalances due to the excessive secretion of pituitary hormones. One such type of pituitary adenoma is prolactin-secreting adenoma, which is caused due to a mutation in the AIP gene. The AIP gene is responsible for encoding a protein that regulates the growth and proliferation of cells. Mutations in this gene can lead to the development of pituitary adenomas.

Symptoms of AIP Gene Pituitary Adenoma

The symptoms of AIP gene pituitary adenoma are similar to those of other pituitary adenomas. These include:

• Headaches
• Visual disturbances
• Fatigue
• Loss of libido
• Infertility
• Irregular menstrual periods
• Breast milk secretion in women who are not pregnant or nursing

In some cases, the tumor may be large enough to compress the surrounding structures, leading to additional symptoms such as:

• Nausea and vomiting
• Dizziness
• Weakness
• Numbness or tingling in the extremities

Diagnosis of AIP Gene Pituitary Adenoma

The diagnosis of AIP gene pituitary adenoma involves a combination of imaging studies and blood tests. The imaging studies include:

• Magnetic resonance imaging (MRI) of the brain: This helps in visualizing the size and location of the tumor.
• Computed tomography (CT) scan: This provides additional information about the tumor and its surrounding structures.
• X-rays: These are used to visualize the bones of the skull and detect any abnormalities.

The blood tests include:

• Prolactin level: Elevated prolactin levels are a hallmark of prolactin-secreting adenomas.
• Growth hormone (GH) level: Elevated GH levels may indicate the presence of a somatotroph adenoma.
• Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels: Abnormal levels of these hormones may indicate the presence of a gonadotroph adenoma.

NGS Genetic DNA Test for AIP Gene Pituitary Adenoma

Next-generation sequencing (NGS) is a powerful tool for detecting genetic mutations associated with pituitary adenomas. This test involves sequencing the entire AIP gene to identify any mutations that may be present. The cost of NGS genetic DNA test for AIP gene pituitary adenoma in India is around INR 20,000.

The NGS test provides several advantages over traditional genetic testing methods. These include:

• Higher accuracy: NGS can detect mutations with a higher degree of accuracy compared to traditional genetic testing methods.
• More comprehensive: NGS can detect multiple mutations in a single test, providing a more comprehensive view of the genetic landscape of the tumor.
• Quicker turnaround time: NGS can provide results in a shorter time frame compared to traditional genetic testing methods.

Conclusion

AIP gene pituitary adenoma is a rare type of pituitary adenoma that is caused due to a mutation in the AIP gene. The symptoms of this condition are similar to those of other pituitary adenomas, and the diagnosis involves a combination of imaging studies and blood tests. NGS genetic DNA testing is a powerful tool for detecting mutations associated with pituitary adenomas, including AIP gene pituitary adenoma. The cost of NGS genetic DNA testing for AIP gene pituitary adenoma in India is around INR 20,000.

If you suspect that you may have AIP gene pituitary adenoma or any other type of pituitary adenoma, it is important to seek medical attention promptly. Early diagnosis and treatment can help prevent complications and improve outcomes.