Short Description

NGS genetic DNA test detecets for variant and mutation detection in AGXT gene for Hyperoxaluria type 1

PreTest Information

Clinical History of Patient who is going for AGXT Gene Hyperoxaluria type 1 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hyperoxaluria type 1

Detail Description

AGXT Gene Hyperoxaluria Type 1 NGS Genetic DNA Test Cost INR 20,000: Symptoms, Diagnosis and Treatment

Hyperoxaluria is a rare genetic disorder that leads to the formation of kidney stones, as well as damage to the kidneys and other organs. The AGXT gene is responsible for the production of an enzyme that helps the body break down oxalate, a substance found in certain foods. When this gene is mutated, it can lead to hyperoxaluria type 1 (PH1).

NGS Genetic DNA Test is a test that looks for changes or mutations in the AGXT gene. This test helps in the diagnosis of PH1 and other genetic disorders. The cost of the test is INR 20,000.

Symptoms of Hyperoxaluria Type 1

PH1 is usually diagnosed in infants or young children. The symptoms of PH1 include:

• Recurrent kidney stones
• Blood in urine
• Pain in the back or side
• Urinary tract infections
• Reduced urine output
• Kidney damage
• Kidney failure

It is important to note that not all people with PH1 will experience all of these symptoms.

Diagnosis of Hyperoxaluria Type 1

If PH1 is suspected, a doctor may order a variety of tests to diagnose the condition. These tests may include:

• Urine tests to check for oxalate crystals
• Blood tests to check kidney function and electrolyte levels
• Imaging tests such as X-rays, CT scans or ultrasounds to check for kidney stones or damage
• Genetic testing to check for mutations in the AGXT gene

The NGS Genetic DNA Test is a highly accurate method of diagnosing PH1.

Treatment of Hyperoxaluria Type 1

There is no cure for PH1, but treatment can help manage the symptoms and prevent complications. Treatment options may include:

• Drinking plenty of fluids to prevent dehydration and reduce the concentration of oxalate in the urine
• Medications to reduce the amount of oxalate produced by the body
• Medications to help dissolve kidney stones
• Surgery to remove large kidney stones or damaged tissue
• Dialysis or kidney transplant in severe cases of kidney damage or failure

Conclusion

Hyperoxaluria type 1 is a rare genetic disorder that can cause kidney stones, kidney damage, and other complications. The AGXT Gene Hyperoxaluria Type 1 NGS Genetic DNA Test is a highly accurate method of diagnosing the condition. The cost of the test is INR 20,000. If you or a loved one is experiencing symptoms of PH1, it is important to speak with a doctor and get tested for the condition.

At DNA Labs India, we provide highly accurate and reliable genetic testing services, including the AGXT Gene Hyperoxaluria Type 1 NGS Genetic DNA Test. Our team of experienced professionals is committed to providing the highest level of care to our patients. Contact us today to learn more about our services.