Short Description

NGS genetic DNA test detecets for variant and mutation detection in AGTR2 gene for Mental retardation, X-linked type 88, AGTR2 related

PreTest Information

Clinical History of Patient who is going for AGTR2 Gene Mental retardation, X-linked type 88, AGTR2 related NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with AGTR2 Gene Mental retardation, X-linked type 88, AGTR2 related

Detail Description

AGTR2 Gene and Mental Retardation: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

AGTR2 gene is a protein-coding gene that is responsible for encoding the angiotensin II receptor type 2. This receptor plays a significant role in regulating blood pressure, fluid balance, and electrolyte homeostasis. However, mutations in this gene have been linked to mental retardation, X-linked type 88.

Symptoms of Mental Retardation Linked to AGTR2 Gene Mutations

The symptoms of mental retardation linked to AGTR2 gene mutations can vary widely. Some of the most common symptoms include:

• Delayed speech and language development
• Delayed motor skills development
• Intellectual disability
• Behavioral abnormalities
• Autistic features
• Hyperactivity
• Seizures

It is important to note that not all individuals with mutations in the AGTR2 gene will exhibit all of these symptoms. The severity of the symptoms can also vary widely, even among individuals with the same mutation.

Diagnosis of Mental Retardation Linked to AGTR2 Gene Mutations

Diagnosis of mental retardation linked to AGTR2 gene mutations typically involves a combination of physical exams, developmental assessments, and genetic testing.

During a physical exam, a healthcare provider will evaluate an individual's physical and neurological development, looking for any signs of delay or abnormalities. A developmental assessment will involve a series of tests to evaluate an individual's cognitive, motor, and language skills.

Genetic testing is the most definitive way to diagnose a mutation in the AGTR2 gene. Next-generation sequencing (NGS) genetic DNA testing is a powerful tool that can identify mutations in large numbers of genes simultaneously. The cost of NGS genetic DNA testing in India typically ranges from INR 15,000 to INR 25,000, with the average cost being around INR 20,000.

Conclusion

Mutations in the AGTR2 gene have been linked to mental retardation, X-linked type 88. The symptoms of this condition can vary widely, and diagnosis typically involves a combination of physical exams, developmental assessments, and genetic testing. NGS genetic DNA testing is a powerful tool that can identify mutations in large numbers of genes simultaneously and is widely available in India at an average cost of INR 20,000.

If you or someone you know is exhibiting symptoms of mental retardation and you suspect a genetic cause, it is important to seek medical attention promptly. With early diagnosis and treatment, individuals with mutations in the AGTR2 gene can receive the support and care they need to reach their full potential.