Short Description

NGS genetic DNA test detecets for variant and mutation detection in AGTR1 gene for Renal tubular dysgenesis

PreTest Information

Clinical History of Patient who is going for AGTR1 Gene Renal tubular dysgenesis NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with AGTR1 Gene Renal tubular dysgenesis NGS Genetic DNA Test gene AGTR1

Detail Description

AGTR1 Gene Renal Tubular Dysgenesis NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

Renal tubular dysgenesis is a rare genetic disorder that affects the development of the kidneys. It is caused by mutations in the AGTR1 gene. This gene provides instructions for making a protein called angiotensin II receptor type 1, which plays a role in the development of blood vessels and the regulation of blood pressure.

Renal tubular dysgenesis is characterized by the underdevelopment of the renal tubules, which are structures in the kidneys that help filter waste from the blood. This can lead to a decrease in the production of urine and a buildup of waste products in the body.

Symptoms of Renal Tubular Dysgenesis

• Low birth weight
• Difficulty feeding
• Decreased urine production
• Dehydration
• Electrolyte imbalances

Diagnosis of Renal Tubular Dysgenesis

Renal tubular dysgenesis is typically diagnosed through genetic testing. DNA Labs India offers an NGS genetic DNA test that can identify mutations in the AGTR1 gene. This test is non-invasive and involves collecting a small sample of blood or saliva from the patient.

NGS Genetic DNA Test Cost

The cost of the NGS genetic DNA test for AGTR1 gene renal tubular dysgenesis at DNA Labs India is INR 20000. This includes the cost of sample collection, analysis, and reporting of results.

Conclusion

If you suspect that you or your child may have renal tubular dysgenesis, it is important to seek medical attention and consider genetic testing. DNA Labs India's NGS genetic DNA test can provide valuable information about the presence of mutations in the AGTR1 gene and help guide treatment and management options.

The AGTR1 gene encodes the angiotensin II type 1 receptor, which is a key component of the renin-angiotensin system involved in regulating blood pressure and various physiological processes. Mutations in the AGTR1 gene can lead to a range of conditions, but as of my last knowledge update in September 2021, there is no known direct association between AGTR1 gene mutations and renal tubular dysgenesis (RTD).

Renal tubular dysgenesis is typically associated with mutations in other genes, such as the AGT gene mentioned in a previous response. AGT encodes angiotensinogen, a precursor protein involved in the production of angiotensin II, which plays a role in kidney development and blood pressure regulation. Mutations in the AGT gene can lead to abnormal kidney development and function, resulting in RTD.

It's important to note that medical knowledge is constantly evolving, and new associations between genes and conditions can be discovered over time. If you are seeking information about a specific genetic test or condition, I recommend consulting with a medical geneticist, genetic counselor, or other healthcare professionals who specialize in genetics. They can provide you with the most up-to-date and accurate information based on the latest research and medical advancements.