Short Description

NGS genetic DNA test detecets for variant and mutation detection in AFF3 gene for Rheumatoid arthritis, susceptibility to

PreTest Information

Clinical History of Patient who is going for AFF3 Gene Rheumatoid arthritis, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with AFF3 Gene Rheumatoid arthritis, susceptibility to NGS Genetic DNA Test gene AFF3

Detail Description

AFF3 Gene and Rheumatoid Arthritis: Understanding Susceptibility through NGS Genetic DNA Test

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that affects the joints, causing inflammation, pain, and stiffness. It is estimated that over 1.3 million people in India suffer from RA, and the disease is more common in women than men.

Researchers have identified several genes that may contribute to the development of RA, including the AFF3 gene. The AFF3 gene is located on chromosome 2 and plays a role in regulating the immune system. Studies have shown that variations in the AFF3 gene may increase a person's susceptibility to RA.

What is NGS Genetic DNA Test?

The Next-Generation Sequencing (NGS) Genetic DNA Test is a cutting-edge technology that allows scientists to sequence an individual's entire genome. This test can identify genetic variations that may contribute to the development of RA, including those in the AFF3 gene.

The NGS Genetic DNA Test is a non-invasive procedure that involves taking a small sample of blood or saliva from the patient. The sample is then sent to a laboratory for analysis, and the results are usually available within a few weeks.

Symptoms and Diagnosis of Rheumatoid Arthritis

Rheumatoid arthritis can cause a variety of symptoms, including:

• Pain, swelling, and stiffness in the joints (particularly in the hands, feet, and wrists)
• Fatigue
• Fever
• Loss of appetite
• Weight loss
• Depression
• Anemia

Diagnosis of RA involves a combination of physical exams, imaging tests, and blood tests. The presence of certain antibodies, such as rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibodies, can indicate the presence of RA.

NGS Genetic DNA Test Cost in India

The cost of the NGS Genetic DNA Test in India can vary depending on the laboratory and the complexity of the analysis. On average, the cost of the test can range from INR 20,000 to INR 50,000.

Conclusion

The AFF3 gene has been identified as a potential contributor to the development of RA. The NGS Genetic DNA Test is a valuable tool for identifying genetic variations that may increase a person's susceptibility to RA. Early detection of RA can lead to better treatment outcomes and improved quality of life. If you are experiencing symptoms of RA or have a family history of the disease, talk to your doctor about the possibility of undergoing the NGS Genetic DNA Test.

At DNA Labs India, we offer the NGS Genetic DNA Test at an affordable cost. Our state-of-the-art laboratory and experienced staff ensure accurate and reliable results. Contact us today to schedule your test.