Short Description

NGS genetic DNA test detecets for variant and mutation detection in ADAMTS13 gene for Thrombotic thrombocytopenic purpura

PreTest Information

Clinical History of Patient who is going for ADAMTS13 Gene Thrombotic thrombocytopenic purpura NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ADAMTS13 Gene Thrombotic thrombocytopenic purpura NGS Genetic DNA Test gene ADAMTS13

Detail Description

ADAMTS13 Gene Thrombotic Thrombocytopenic Purpura NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

• Home
• About Us
• Services
• Contact Us

Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder that affects the small blood vessels in the body. It is caused by a deficiency of the ADAMTS13 enzyme, which is responsible for breaking down von Willebrand factor (vWF) in the blood. When vWF is not broken down properly, it can form clumps in the blood vessels, leading to the formation of blood clots and damage to the organs.

The ADAMTS13 gene provides instructions for making the ADAMTS13 enzyme. Mutations in this gene can cause a deficiency of the enzyme, leading to TTP. The ADAMTS13 gene can be analyzed using next-generation sequencing (NGS) technology to identify mutations that may be responsible for TTP.

Symptoms of TTP

The symptoms of TTP can include:

• Small red or purple spots on the skin, called purpura
• Fever
• Fatigue
• Weakness
• Headache
• Confusion
• Seizures
• Coma

Diagnosis of TTP

TTP is diagnosed through a combination of medical history, physical examination, and laboratory tests. These tests may include:

• Complete blood count (CBC)
• Blood smear
• Blood chemistry tests
• ADAMTS13 activity assay
• ADAMTS13 antibody assay

ADAMTS13 Gene NGS Genetic DNA Test Cost INR:20000

The ADAMTS13 gene NGS genetic DNA test cost is INR:20000 at DNA Labs India. This test uses next-generation sequencing (NGS) technology to analyze the ADAMTS13 gene and identify mutations that may be responsible for TTP. The test is performed on a blood or saliva sample and takes approximately 2-3 weeks to complete.

If you are experiencing symptoms of TTP or have a family history of the condition, it is important to speak with your healthcare provider about getting tested. Early diagnosis and treatment can improve outcomes and prevent complications.