Short Description

NGS genetic DNA test detecets for variant and mutation detection in ADAM10 gene for Reticulate acropigmentation of Kitamura

PreTest Information

Clinical History of Patient who is going for ADAM10 Gene Reticulate acropigmentation of Kitamura NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ADAM10 Gene Reticulate acropigmentation of Kitamura NGS Genetic DNA Test gene ADAM10

Detail Description

ADAM10 Gene Reticulate Acropigmentation of Kitamura NGS Genetic DNA Test

ADAM10 gene reticulate acropigmentation of Kitamura is a rare genetic skin disorder that affects the pigmentation of the skin. This condition is caused by a mutation in the ADAM10 gene, which provides instructions for producing a protein called a disintegrin and metalloproteinase domain-containing protein 10. This protein is involved in the processing of other proteins that play a role in cell signaling and cell adhesion.

Symptoms

The symptoms of ADAM10 gene reticulate acropigmentation of Kitamura usually appear in infancy or childhood. The affected individuals develop reticulated or net-like hyperpigmentation on the hands and feet, which tends to spread over time to involve other parts of the body. The hyperpigmentation is usually more pronounced in areas exposed to sunlight. In some cases, the affected individuals may also have small white spots on the skin, which are known as guttate hypomelanosis.

Diagnosis

The diagnosis of ADAM10 gene reticulate acropigmentation of Kitamura is usually based on the clinical presentation of the hyperpigmentation. However, genetic testing can confirm the diagnosis by identifying the mutation in the ADAM10 gene. Next-generation sequencing (NGS) is a powerful tool that can sequence the entire ADAM10 gene and identify any mutations present. This test is highly accurate and can detect mutations that may be missed by other methods.

Cost of NGS Genetic DNA Test

The cost of the NGS genetic DNA test for ADAM10 gene reticulate acropigmentation of Kitamura in India is approximately INR 20,000. This cost may vary depending on the laboratory and location.

Conclusion

ADAM10 gene reticulate acropigmentation of Kitamura is a rare genetic skin disorder that can be diagnosed through genetic testing. NGS is a highly accurate method for identifying mutations in the ADAM10 gene. The cost of the NGS genetic DNA test for this condition in India is approximately INR 20,000. Early diagnosis and management of this condition can help improve the quality of life for affected individuals.

If you suspect that you or your child may have ADAM10 gene reticulate acropigmentation of Kitamura, it is important to seek medical advice and genetic testing. DNA Labs India offers a range of genetic tests for various conditions, including ADAM10 gene reticulate acropigmentation of Kitamura. Contact us today to learn more about our services.