Short Description

Myasthenia gravis (MG) is characterised by muscle weakness & easy fatigability most commonly due to autoantibody mediated loss of functional acetylcholine receptors in the postsynaptic membrane of skeletal muscle. ACHR antibodies are not found in Congenital MG. This assay is used to diagnose Acquired forms of MG (90% positive), for detecting subclinical MG in recipients of D-penicillamine, Thymoma without clinical evidence of MG & Graft versus Host disease. It may also be positive in Lambert-Eaton myasthenic syndrome, Autoimmune liver disease & Paraneoplastic autoimmune neurological disorders.

PreTest Information

Avoid general anaesthetic or muscle relaxant drugs 24 hours prior to sampling. This assay should not be requested for patients who have recently received radio-isotopes therapeutically or diagnostically due to potential assay interference.

Detail Description

ACETYLCHOLINE RECEPTOR (ACHR) BINDING ANTIBODY Test: Cost, Symptoms, and Diagnosis

DNA Labs India offers the Acetylcholine Receptor (AChR) Binding Antibody Test to diagnose autoimmune disorders that affect the neuromuscular junction. This test determines the presence of autoantibodies that attack the AChR, which is responsible for transmitting nerve impulses to muscles.

Test Cost

The AChR Binding Antibody Test cost at DNA Labs India is INR 3500. The test requires a blood sample, which is analyzed in the laboratory.

Symptoms

Autoimmune disorders that affect the neuromuscular junction can cause a range of symptoms, including:

• Muscle weakness
• Fatigue
• Difficulty breathing
• Difficulty swallowing
• Double vision

These symptoms can be mild or severe and may worsen over time. If you experience any of these symptoms, you should consult a doctor as soon as possible.

Diagnosis

Diagnosing autoimmune disorders that affect the neuromuscular junction can be challenging, as symptoms may be similar to other conditions. Doctors usually start with a physical examination and medical history review to identify any underlying conditions. Blood tests, such as the AChR Binding Antibody Test, can help confirm a diagnosis.

If the test results are positive, further testing may be required to determine the specific autoimmune disorder and its severity. Treatment options may include medication, physical therapy, or surgery, depending on the individual's needs.

Conclusion

The Acetylcholine Receptor (AChR) Binding Antibody Test is a valuable tool for diagnosing autoimmune disorders that affect the neuromuscular junction. DNA Labs India offers this test at an affordable cost of INR 3500. If you are experiencing any symptoms of muscle weakness or difficulty breathing, consult a doctor immediately to get a proper diagnosis and treatment.

For more information or to schedule a test, contact DNA Labs India today.