Short Description

NGS genetic DNA test detecets for variant and mutation detection in ABCC2 gene for Dubin-Johnson syndrome

PreTest Information

Clinical History of Patient who is going for ABCC2 Gene Dubin-Johnson syndrome NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ABCC2 Gene Dubin-Johnson syndrome NGS Genetic DNA Test gene ABCC2

Detail Description

ABCC2 Gene Dubin-Johnson Syndrome NGS Genetic DNA Test Cost INR: 20000 Symptoms Diagnosis

What is ABCC2 Gene Dubin-Johnson Syndrome?

ABCC2 Gene Dubin-Johnson Syndrome is a rare, inherited disorder that affects the liver's ability to process certain substances. This condition is caused by mutations in the ABCC2 gene, which provides instructions for making a protein called multidrug resistance-associated protein 2 (MRP2). MRP2 plays a critical role in moving substances, including bilirubin, out of liver cells and into bile. In people with ABCC2 Gene Dubin-Johnson Syndrome, MRP2 is not produced or does not function properly, resulting in a buildup of bilirubin in the liver and bloodstream.

What are the Symptoms of ABCC2 Gene Dubin-Johnson Syndrome?

The symptoms of ABCC2 Gene Dubin-Johnson Syndrome can vary widely. Some people with the condition may have no symptoms, while others may experience:

• Yellowing of the skin and eyes (jaundice)
• Fatigue
• Abdominal pain and swelling
• Itching
• Dark urine

How is ABCC2 Gene Dubin-Johnson Syndrome Diagnosed?

ABCC2 Gene Dubin-Johnson Syndrome is typically diagnosed through genetic testing. This involves analyzing a sample of the patient's DNA to look for mutations in the ABCC2 gene. Other tests, such as liver function tests and imaging studies, may also be used to help diagnose the condition and rule out other liver disorders.

What is NGS Genetic DNA Test?

NGS (Next-Generation Sequencing) Genetic DNA Test is a type of genetic test that uses cutting-edge technology to analyze a patient's DNA. This test can identify changes or mutations in the DNA that may be causing a particular condition, such as ABCC2 Gene Dubin-Johnson Syndrome. NGS can also be used to analyze large sections of the genome at once, making it a powerful tool for genetic research and diagnosis.

What is the Cost of NGS Genetic DNA Test for ABCC2 Gene Dubin-Johnson Syndrome?

The cost of NGS Genetic DNA Test for ABCC2 Gene Dubin-Johnson Syndrome is INR 20000 at DNA Labs India. This cost includes the genetic testing, interpretation of the results, and genetic counseling with a board-certified genetic counselor.