Short Description

NGS genetic DNA test detecets for variant and mutation detection in ABCB4 gene for Cholestasis progressive intrahepatic type 3

PreTest Information

Clinical History of Patient who is going for ABCB4 Gene Cholestasis progressive intrahepatic type 3 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Cholestasis progressive intrahepatic type 3

Detail Description

ABCB4 Gene Cholestasis Progressive Intrahepatic Type 3 NGS Genetic DNA Test

Cholestasis is a liver condition that prevents bile from flowing out of the liver. When this happens, the bile builds up in the liver and can cause damage to liver cells. There are many different types of cholestasis, including progressive intrahepatic cholestasis (PIC). PIC is caused by a genetic mutation that affects the way bile is transported out of the liver. One of the genes that can cause PIC is the ABCB4 gene.

The ABCB4 gene provides instructions for making a protein that is involved in the transport of bile out of the liver. Mutations in this gene can cause the protein to be less effective, which can lead to a buildup of bile in the liver and the development of cholestasis.

Symptoms

The symptoms of ABCB4 gene cholestasis progressive intrahepatic type 3 can vary from person to person. Some people may not experience any symptoms at all, while others may have severe symptoms. The most common symptoms of ABCB4 gene cholestasis progressive intrahepatic type 3 include:

• Jaundice
• Itching
• Enlarged liver and spleen
• Abdominal pain
• Low platelet count
• Delayed growth

Diagnosis

If you are experiencing symptoms of ABCB4 gene cholestasis progressive intrahepatic type 3, your doctor may recommend a genetic test to confirm the diagnosis. The NGS Genetic DNA Test is a type of genetic test that can identify mutations in the ABCB4 gene. This test involves taking a small sample of blood or tissue and analyzing the DNA to look for mutations in the ABCB4 gene.

Cost

The cost of the NGS Genetic DNA Test for ABCB4 gene cholestasis progressive intrahepatic type 3 can vary depending on where you have the test done. In India, the cost of the test is typically around INR 20,000. It is important to check with your insurance provider to see if the test is covered under your plan.

Conclusion

ABCB4 gene cholestasis progressive intrahepatic type 3 is a rare liver condition caused by a genetic mutation in the ABCB4 gene. If you are experiencing symptoms of cholestasis, it is important to talk to your doctor about the possibility of a genetic test to confirm the diagnosis. The NGS Genetic DNA Test is a reliable and accurate test that can help diagnose ABCB4 gene cholestasis progressive intrahepatic type 3. While the cost of the test can vary, it is an important investment in your health and wellbeing.

At DNA Labs India, we offer a wide range of genetic testing services to help diagnose and manage a variety of conditions. Contact us today to learn more about our services and how we can help you.