Short Description

NGS genetic DNA test detecets for variant and mutation detection in ABCB4 gene for Cholestasis intrahepatic, of pregnancy, type 3

PreTest Information

Clinical History of Patient who is going for ABCB4 Gene Cholestasis intrahepatic, of pregnancy, type 3 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Cholestasis intrahepatic, of pregnancy, type 3

Detail Description

ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 NGS Genetic DNA Test - Symptoms, Diagnosis, and Cost

Cholestasis Intrahepatic of Pregnancy (ICP) is a liver disorder that occurs during pregnancy. The disorder is characterized by a decreased flow of bile, which leads to the buildup of bile acids in the bloodstream. This buildup can cause severe itching, jaundice, and other complications. There are several types of ICP, and one of them is caused by mutations in the ABCB4 gene, which is responsible for the production of a protein called MDR3. This type of ICP is known as ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3.

Symptoms of ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3

The symptoms of ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 are similar to other types of ICP. The most common symptom is severe itching, which usually begins on the palms of the hands and soles of the feet and can spread to other parts of the body. Other symptoms include:

• Dark urine
• Pale stools
• Jaundice
• Nausea and vomiting
• Loss of appetite

If you experience any of these symptoms during pregnancy, it is important to consult your doctor immediately.

Diagnosis of ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3

The diagnosis of ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 is made through a blood test that measures the levels of bile acids in the bloodstream. If the levels are abnormally high, genetic testing may be recommended to confirm the diagnosis. Genetic testing involves analyzing a sample of your DNA to look for mutations in the ABCB4 gene.

NGS Genetic DNA Test for ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3

Next-Generation Sequencing (NGS) is a DNA sequencing technology that allows for the rapid and accurate analysis of large amounts of DNA. NGS can be used to analyze the entire coding region of the ABCB4 gene to identify any mutations that may be causing ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3. The test is highly accurate and can provide results in a matter of days.

Cost of ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 NGS Genetic DNA Test

The cost of the ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 NGS Genetic DNA Test in India is approximately INR 20,000. The cost may vary depending on the location and the laboratory where the test is performed. It is important to consult with your doctor or a genetic counselor to determine if this test is appropriate for you and to discuss the potential costs and insurance coverage.

Conclusion

ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 is a rare but serious liver disorder that can occur during pregnancy. If you experience any symptoms of ICP, it is important to consult with your doctor immediately. Genetic testing, including NGS, can provide an accurate diagnosis and help guide treatment options. The cost of the ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 NGS Genetic DNA Test may vary, but it is an important investment in your health and the health of your baby.

At DNA Labs India, we offer a wide range of genetic testing services, including the ABCB4 Gene Cholestasis Intrahepatic of Pregnancy Type 3 NGS Genetic DNA Test. Our team of expert genetic counselors and scientists is committed to providing accurate and timely results to help you make informed decisions about your health and the health of your family. Contact us today to learn more about our services.